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Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).
Gustafsson MO, Hussain A, Mohammad DK, Mohamed AJ, Nguyen V, Metalnikov P, Colwill K, Pawson T, Smith CI, Nore BF. Gustafsson MO, et al. Among authors: colwill k. Mol Cell Biol. 2012 Jul;32(13):2440-53. doi: 10.1128/MCB.06620-11. Epub 2012 Apr 23. Mol Cell Biol. 2012. PMID: 22527282 Free PMC article.
Defining the specificity space of the human SRC homology 2 domain.
Huang H, Li L, Wu C, Schibli D, Colwill K, Ma S, Li C, Roy P, Ho K, Songyang Z, Pawson T, Gao Y, Li SS. Huang H, et al. Among authors: colwill k. Mol Cell Proteomics. 2008 Apr;7(4):768-84. doi: 10.1074/mcp.M700312-MCP200. Epub 2007 Oct 22. Mol Cell Proteomics. 2008. PMID: 17956856 Free article.
ProHits: integrated software for mass spectrometry-based interaction proteomics.
Liu G, Zhang J, Larsen B, Stark C, Breitkreutz A, Lin ZY, Breitkreutz BJ, Ding Y, Colwill K, Pasculescu A, Pawson T, Wrana JL, Nesvizhskii AI, Raught B, Tyers M, Gingras AC. Liu G, et al. Among authors: colwill k. Nat Biotechnol. 2010 Oct;28(10):1015-7. doi: 10.1038/nbt1010-1015. Nat Biotechnol. 2010. PMID: 20944583 Free PMC article. No abstract available.
Temporal regulation of EGF signalling networks by the scaffold protein Shc1.
Zheng Y, Zhang C, Croucher DR, Soliman MA, St-Denis N, Pasculescu A, Taylor L, Tate SA, Hardy WR, Colwill K, Dai AY, Bagshaw R, Dennis JW, Gingras AC, Daly RJ, Pawson T. Zheng Y, et al. Among authors: colwill k. Nature. 2013 Jul 11;499(7457):166-71. doi: 10.1038/nature12308. Nature. 2013. PMID: 23846654 Free PMC article.
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller PM, Rademacher J, Bagshaw RD, Wortmann C, Barth C, van Unen J, Alp KM, Giudice G, Eccles RL, Heinrich LE, Pascual-Vargas P, Sanchez-Castro M, Brandenburg L, Mbamalu G, Tucholska M, Spatt L, Czajkowski MT, Welke RW, Zhang S, Nguyen V, Rrustemi T, Trnka P, Freitag K, Larsen B, Popp O, Mertins P, Gingras AC, Roth FP, Colwill K, Bakal C, Pertz O, Pawson T, Petsalaki E, Rocks O. Müller PM, et al. Among authors: colwill k. Nat Cell Biol. 2020 Apr;22(4):498-511. doi: 10.1038/s41556-020-0488-x. Epub 2020 Mar 23. Nat Cell Biol. 2020. PMID: 32203420
Functional characterization of a PROTAC directed against BRAF mutant V600E.
Posternak G, Tang X, Maisonneuve P, Jin T, Lavoie H, Daou S, Orlicky S, Goullet de Rugy T, Caldwell L, Chan K, Aman A, Prakesch M, Poda G, Mader P, Wong C, Maier S, Kitaygorodsky J, Larsen B, Colwill K, Yin Z, Ceccarelli DF, Batey RA, Taipale M, Kurinov I, Uehling D, Wrana J, Durocher D, Gingras AC, Al-Awar R, Therrien M, Sicheri F. Posternak G, et al. Among authors: colwill k. Nat Chem Biol. 2020 Nov;16(11):1170-1178. doi: 10.1038/s41589-020-0609-7. Epub 2020 Aug 10. Nat Chem Biol. 2020. PMID: 32778845 Free PMC article.
80 results