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Improved health by combining dietary restriction and promoting muscle growth in DNA repair-deficient progeroid mice.
Vermeij WP, Alyodawi K, van Galen I, von der Heide JL, Birkisdóttir MB, Van't Sant LJ, Ozinga RA, Komninos DSJ, Smit K, Rijksen YMA, Brandt RMC, Barnhoorn S, Jaarsma D, Vaiyapuri S, Ritvos O, Huber TB, Kretz O, Patel K. Vermeij WP, et al. J Cachexia Sarcopenia Muscle. 2024 Dec;15(6):2361-2374. doi: 10.1002/jcsm.13570. Epub 2024 Sep 8. J Cachexia Sarcopenia Muscle. 2024. PMID: 39245994 Free PMC article.
Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.
Alyodawi K, Vermeij WP, Omairi S, Kretz O, Hopkinson M, Solagna F, Joch B, Brandt RMC, Barnhoorn S, van Vliet N, Ridwan Y, Essers J, Mitchell R, Morash T, Pasternack A, Ritvos O, Matsakas A, Collins-Hooper H, Huber TB, Hoeijmakers JHJ, Patel K. Alyodawi K, et al. Among authors: vermeij wp. J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):662-686. doi: 10.1002/jcsm.12404. Epub 2019 Mar 27. J Cachexia Sarcopenia Muscle. 2019. PMID: 30916493 Free PMC article.
Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice.
He Y, Yang W, Huang L, Mever MA, Ramautar R, Harms A, Rijksen Y, Brandt RMC, Barnhoorn S, Smit K, Jaarsma D, Lindenburg P, Hoeijmakers JHJ, Vermeij WP, Hankemeier T. He Y, et al. Among authors: vermeij wp. J Cachexia Sarcopenia Muscle. 2024 Jun;15(3):868-882. doi: 10.1002/jcsm.13433. Epub 2024 Apr 30. J Cachexia Sarcopenia Muscle. 2024. PMID: 38689513 Free PMC article.
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice.
Birkisdóttir MB, Jaarsma D, Brandt RMC, Barnhoorn S, van Vliet N, Imholz S, van Oostrom CT, Nagarajah B, Portilla Fernández E, Roks AJM, Elgersma Y, van Steeg H, Ferreira JA, Pennings JLA, Hoeijmakers JHJ, Vermeij WP, Dollé MET. Birkisdóttir MB, et al. Among authors: vermeij wp. Aging Cell. 2021 Feb;20(2):e13302. doi: 10.1111/acel.13302. Epub 2021 Jan 23. Aging Cell. 2021. PMID: 33484480 Free PMC article.
The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. Birkisdóttir MB, et al. Among authors: vermeij wp. Front Aging. 2022 Oct 12;3:1005322. doi: 10.3389/fragi.2022.1005322. eCollection 2022. Front Aging. 2022. PMID: 36313181 Free PMC article.
Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. Birkisdóttir MB, et al. Among authors: vermeij wp. Front Aging. 2022 Nov 23;3:1086552. doi: 10.3389/fragi.2022.1086552. eCollection 2022. Front Aging. 2022. PMID: 36506463 Free PMC article.
Gene expression changes in cerebellum induced by dietary restriction.
Van't Sant LJ, Birkisdóttir MB, Ozinga RA, Gyenis Á, Hoeijmakers JHJ, Vermeij WP, Jaarsma D. Van't Sant LJ, et al. Among authors: vermeij wp. Front Mol Neurosci. 2023 May 24;16:1185665. doi: 10.3389/fnmol.2023.1185665. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37293544 Free PMC article.
Chemotherapy Side-Effects: Not All DNA Damage Is Equal.
van den Boogaard WMC, Komninos DSJ, Vermeij WP. van den Boogaard WMC, et al. Among authors: vermeij wp. Cancers (Basel). 2022 Jan 26;14(3):627. doi: 10.3390/cancers14030627. Cancers (Basel). 2022. PMID: 35158895 Free PMC article. Review.
47 results