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Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types.
Maggiore JC, LeGraw R, Przepiorski A, Velazquez J, Chaney C, Streeter E, Silva-Barbosa A, Franks J, Hislop J, Hill A, Wu H, Pfister K, Howden SE, Watkins SC, Little M, Humphreys BD, Watson A, Stolz DB, Kiani S, Davidson AJ, Carroll TJ, Cleaver O, Sims-Lucas S, Ebrahimkhani MR, Hukriede NA. Maggiore JC, et al. Among authors: humphreys bd. bioRxiv [Preprint]. 2023 May 30:2023.05.30.542848. doi: 10.1101/2023.05.30.542848. bioRxiv. 2023. Update in: Kidney Int. 2024 Dec;106(6):1086-1100. doi: 10.1016/j.kint.2024.05.026 PMID: 37333155 Free PMC article. Updated. Preprint.
A genetically inducible endothelial niche enables vascularization of human kidney organoids with multilineage maturation and emergence of renin expressing cells.
Maggiore JC, LeGraw R, Przepiorski A, Velazquez J, Chaney C, Vanichapol T, Streeter E, Almuallim Z, Oda A, Chiba T, Silva-Barbosa A, Franks J, Hislop J, Hill A, Wu H, Pfister K, Howden SE, Watkins SC, Little MH, Humphreys BD, Kiani S, Watson A, Stolz DB, Davidson AJ, Carroll T, Cleaver O, Sims-Lucas S, Ebrahimkhani MR, Hukriede NA. Maggiore JC, et al. Among authors: humphreys bd. Kidney Int. 2024 Dec;106(6):1086-1100. doi: 10.1016/j.kint.2024.05.026. Epub 2024 Jun 18. Kidney Int. 2024. PMID: 38901605 Free article.
225 results