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359 results

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Page 1
Antibiotic use during influenza infection augments lung eosinophils that impair immunity against secondary bacterial pneumonia.
Sanches Santos Rizzo Zuttion M, Parimon T, Bora SA, Yao C, Lagree K, Gao CA, Wunderink RG, Kitsios GD, Morris A, Zhang Y, McVerry BJ, Modes ME, Marchevsky AM, Stripp BR, Soto CM, Wang Y, Merene K, Cho S, Victor BL, Vujkovic-Cvijin I, Gupta S, Cassel SL, Sutterwala FS, Devkota S, Underhill DM, Chen P. Sanches Santos Rizzo Zuttion M, et al. Among authors: wunderink rg. J Clin Invest. 2024 Sep 10;134(21):e180986. doi: 10.1172/JCI180986. J Clin Invest. 2024. PMID: 39255040 Free PMC article.
Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19.
Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM, Rasmussen L, Schneider D, Starren J, Donnelly HK, Donayre A, Luo Y, Budinger GRS, Wunderink RG, Misharin AV, Singer BD; NU SCRIPT Study Investigators. Gao CA, et al. Among authors: wunderink rg. J Clin Invest. 2023 Jun 15;133(12):e170682. doi: 10.1172/JCI170682. J Clin Invest. 2023. PMID: 37104035 Free PMC article.
An Adjudication Protocol for Severe Pneumonia.
Pickens CI, Gao CA, Bodner J, Walter JM, Kruser JM, Donnelly HK, Donayre A, Clepp K, Borkowski N, Wunderink RG, Singer BD; NU SCRIPT Study Investigators. Pickens CI, et al. Among authors: wunderink rg. Open Forum Infect Dis. 2023 Jul 1;10(7):ofad336. doi: 10.1093/ofid/ofad336. eCollection 2023 Jul. Open Forum Infect Dis. 2023. PMID: 37520413 Free PMC article.
Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension.
National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; Shapiro NI, Douglas IS, Brower RG, Brown SM, Exline MC, Ginde AA, Gong MN, Grissom CK, Hayden D, Hough CL, Huang W, Iwashyna TJ, Jones AE, Khan A, Lai P, Liu KD, Miller CD, Oldmixon K, Park PK, Rice TW, Ringwood N, Semler MW, Steingrub JS, Talmor D, Thompson BT, Yealy DM, Self WH. National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network, et al. N Engl J Med. 2023 Feb 9;388(6):499-510. doi: 10.1056/NEJMoa2212663. Epub 2023 Jan 21. N Engl J Med. 2023. PMID: 36688507 Free PMC article. Clinical Trial.
Prolonged exposure to lung-derived cytokines is associated with inflammatory activation of microglia in patients with COVID-19.
Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GS. Grant RA, et al. Among authors: wunderink rg. bioRxiv [Preprint]. 2023 Jul 28:2023.07.28.550765. doi: 10.1101/2023.07.28.550765. bioRxiv. 2023. Update in: JCI Insight. 2024 Mar 19;9(8):e178859. doi: 10.1172/jci.insight.178859 PMID: 37546860 Free PMC article. Updated. Preprint.
Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19.
Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Simons LM, Ozer EA, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GRS; Northwestern University Successful Clinical Response In Pneumonia Therapy (NU SCRIPT) Investigators. Grant RA, et al. Among authors: wunderink rg. JCI Insight. 2024 Mar 19;9(8):e178859. doi: 10.1172/jci.insight.178859. JCI Insight. 2024. PMID: 38502186 Free PMC article.
Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.
Alipanah-Lechner N, Hurst-Hopf J, Delucchi K, Swigart L, Willmore A, LaCombe B, Dewar R, Lane HC, Lallemand P, Liu KD, Esserman L, Matthay MA, Calfee CS; I-SPY COVID Consortium. Alipanah-Lechner N, et al. Crit Care. 2024 Feb 21;28(1):56. doi: 10.1186/s13054-024-04819-0. Crit Care. 2024. PMID: 38383504 Free PMC article. Clinical Trial.
359 results