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Page 1
Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.
Hamano J, Higashibata T, Kessoku T, Kajiura S, Hirakawa M, Oyamada S, Ariyoshi K, Yamada T, Yamamoto Y, Takashima Y, Doki K, Homma M, Mathis BJ, Jono T, Ogata T, Tanaka K, Kasai Y, Iwaki M, Fuyuki A, Nakajima A, Hayashi R, Ando T, Izawa N, Kobayashi Y, Horie Y, Morita T. Hamano J, et al. Among authors: tanaka k. J Clin Oncol. 2024 Dec 10;42(35):4206-4217. doi: 10.1200/JCO.24.00381. Epub 2024 Sep 10. J Clin Oncol. 2024. PMID: 39255425 Free PMC article. Clinical Trial.
The Role of Leaky Gut in Nonalcoholic Fatty Liver Disease: A Novel Therapeutic Target.
Kessoku T, Kobayashi T, Tanaka K, Yamamoto A, Takahashi K, Iwaki M, Ozaki A, Kasai Y, Nogami A, Honda Y, Ogawa Y, Kato S, Imajo K, Higurashi T, Hosono K, Yoneda M, Usuda H, Wada K, Saito S, Nakajima A. Kessoku T, et al. Among authors: tanaka k. Int J Mol Sci. 2021 Jul 29;22(15):8161. doi: 10.3390/ijms22158161. Int J Mol Sci. 2021. PMID: 34360923 Free PMC article. Review.
Endotoxins and Non-Alcoholic Fatty Liver Disease.
Kessoku T, Kobayashi T, Imajo K, Tanaka K, Yamamoto A, Takahashi K, Kasai Y, Ozaki A, Iwaki M, Nogami A, Honda Y, Ogawa Y, Kato S, Higurashi T, Hosono K, Yoneda M, Okamoto T, Usuda H, Wada K, Kobayashi N, Saito S, Nakajima A. Kessoku T, et al. Among authors: tanaka k. Front Endocrinol (Lausanne). 2021 Oct 29;12:770986. doi: 10.3389/fendo.2021.770986. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34777261 Free PMC article. Review.
Effectiveness of Naldemedine Compared with Magnesium Oxide in Preventing Opioid-Induced Constipation: A Randomized Controlled Trial.
Ozaki A, Kessoku T, Tanaka K, Yamamoto A, Takahashi K, Takeda Y, Kasai Y, Iwaki M, Kobayashi T, Yoshihara T, Kato T, Suzuki A, Honda Y, Ogawa Y, Fuyuki A, Imajo K, Higurashi T, Yoneda M, Taguri M, Ishiki H, Kobayashi N, Saito S, Ichikawa Y, Nakajima A. Ozaki A, et al. Among authors: tanaka k. Cancers (Basel). 2022 Apr 24;14(9):2112. doi: 10.3390/cancers14092112. Cancers (Basel). 2022. PMID: 35565243 Free PMC article.
Association of Serum and Fecal Bile Acid Patterns With Liver Fibrosis in Biopsy-Proven Nonalcoholic Fatty Liver Disease: An Observational Study.
Kasai Y, Kessoku T, Tanaka K, Yamamoto A, Takahashi K, Kobayashi T, Iwaki M, Ozaki A, Nogami A, Honda Y, Ogawa Y, Kato S, Imajo K, Higurashi T, Hosono K, Yoneda M, Usuda H, Wada K, Kawanaka M, Kawaguchi T, Torimura T, Kage M, Hyogo H, Takahashi H, Eguchi Y, Aishima S, Kobayashi N, Sumida Y, Honda A, Oyamada S, Shinoda S, Saito S, Nakajima A. Kasai Y, et al. Among authors: tanaka k. Clin Transl Gastroenterol. 2022 Jul 1;13(7):e00503. doi: 10.14309/ctg.0000000000000503. Epub 2022 May 26. Clin Transl Gastroenterol. 2022. PMID: 35616321 Free PMC article.
Rationale and design of a multicentre, 12-week, randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated trial to investigate the efficacy and safety of elobixibat for chronic constipation.
Tanaka K, Kessoku T, Yamamoto A, Takahashi K, Kasai Y, Ozaki A, Iwaki M, Kobayashi T, Yoshihara T, Misawa N, Kato T, Arimoto J, Fuyuki A, Sakai E, Higurashi T, Chiba H, Hosono K, Yoneda M, Iwasaki T, Kurihashi T, Nakatogawa M, Suzuki A, Taguri M, Oyamada S, Ariyoshi K, Kobayashi N, Ichikawa Y, Nakajima A. Tanaka K, et al. BMJ Open. 2022 May 30;12(5):e060704. doi: 10.1136/bmjopen-2021-060704. BMJ Open. 2022. PMID: 35636802 Free PMC article. Clinical Trial.
Rationale and design of a multicenter, single-group, open-label trial aiming at investigating the effectiveness of elobixibat for loss of defecation desire in patients with chronic constipation.
Yamamoto A, Kessoku T, Tanaka K, Takahashi K, Kasai Y, Ozaki A, Iwaki M, Kobayashi T, Yoshihara T, Misawa N, Ohkuma K, Fuyuki A, Higurashi T, Hosono K, Yoneda M, Iwasaki T, Kurihashi T, Nakatogawa M, Suzuki A, Taguri M, Oyamada S, Ariyoshi K, Kobayashi N, Ichikawa Y, Nakajima A. Yamamoto A, et al. Among authors: tanaka k. Contemp Clin Trials Commun. 2022 Jun 27;28:100958. doi: 10.1016/j.conctc.2022.100958. eCollection 2022 Aug. Contemp Clin Trials Commun. 2022. PMID: 35812817 Free PMC article.
Efficacy and safety of guanabenz acetate treatment for non-alcoholic fatty liver disease: a study protocol for a randomised investigator-initiated phase IIa study.
Iwaki M, Kessoku T, Tanaka K, Ozaki A, Kasai Y, Yamamoto A, Takahashi K, Kobayashi T, Nogami A, Honda Y, Ogawa Y, Imajo K, Yoneda M, Kobayashi N, Saito S, Nakajima A. Iwaki M, et al. Among authors: tanaka k. BMJ Open. 2022 Jul 12;12(7):e060335. doi: 10.1136/bmjopen-2021-060335. BMJ Open. 2022. PMID: 35820743 Free PMC article.
Comparison of long-term prognosis between non-obese and obese patients with non-alcoholic fatty liver disease.
Iwaki M, Kessoku T, Tanaka K, Ozaki A, Kasai Y, Yamamoto A, Takahashi K, Kobayashi T, Nogami A, Honda Y, Ogawa Y, Imajo K, Oyamada S, Kobayashi N, Aishima S, Saito S, Nakajima A, Yoneda M. Iwaki M, et al. Among authors: tanaka k. JGH Open. 2022 Aug 24;6(10):696-703. doi: 10.1002/jgh3.12808. eCollection 2022 Oct. JGH Open. 2022. PMID: 36262543 Free PMC article.
Natural History of Chronic Intestinal Pseudo-obstruction and Need for Palliative Care.
Tanaka K, Ohkubo H, Yamamoto A, Takahashi K, Kasai Y, Ozaki A, Iwaki M, Kobayashi T, Yoshihara T, Misawa N, Fuyuki A, Kato S, Higurashi T, Hosono K, Yoneda M, Kurihashi T, Taguri M, Nakajima A, Gwee KA, Kessoku T. Tanaka K, et al. J Neurogastroenterol Motil. 2023 Jul 30;29(3):378-387. doi: 10.5056/jnm22152. J Neurogastroenterol Motil. 2023. PMID: 37417265 Free PMC article.
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