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Molecular imaging in experimental pulmonary fibrosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltration.
Farooq H, Luehmann HP, Koenitzer JR, Heo GS, Sultan DH, Kulkarni DH, Gunsten SP, Sashti RM, Huang T, Keller AR, Lavine KJ, Atkinson JJ, Wingler LM, Liu Y, Brody SL. Farooq H, et al. Among authors: wingler lm. EBioMedicine. 2024 Dec;110:105431. doi: 10.1016/j.ebiom.2024.105431. Epub 2024 Nov 7. EBioMedicine. 2024. PMID: 39515027 Free PMC article.
Progress on the development of Class A GPCR-biased ligands.
Morales P, Scharf MM, Bermudez M, Egyed A, Franco R, Hansen OK, Jagerovic N, Jakubík J, Keserű GM, Kiss DJ, Kozielewicz P, Larsen O, Majellaro M, Mallo-Abreu A, Navarro G, Prieto-Díaz R, Rosenkilde MM, Sotelo E, Stark H, Werner T, Wingler LM. Morales P, et al. Among authors: wingler lm. Br J Pharmacol. 2024 Sep 11. doi: 10.1111/bph.17301. Online ahead of print. Br J Pharmacol. 2024. PMID: 39261899 Review.
Antibodies expand the scope of angiotensin receptor pharmacology.
Skiba MA, Sterling SM, Rawson S, Zhang S, Xu H, Jiang H, Nemeth GR, Gilman MSA, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Rockman HA, Barth P, Wingler LM, Kruse AC. Skiba MA, et al. Among authors: wingler lm. Nat Chem Biol. 2024 Dec;20(12):1577-1585. doi: 10.1038/s41589-024-01620-6. Epub 2024 May 14. Nat Chem Biol. 2024. PMID: 38744986
Antibodies Expand the Scope of Angiotensin Receptor Pharmacology.
Skiba MA, Sterling SM, Rawson S, Gilman MSA, Xu H, Nemeth GR, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Wingler LM, Kruse AC. Skiba MA, et al. Among authors: wingler lm. bioRxiv [Preprint]. 2023 Aug 24:2023.08.23.554128. doi: 10.1101/2023.08.23.554128. bioRxiv. 2023. Update in: Nat Chem Biol. 2024 Dec;20(12):1577-1585. doi: 10.1038/s41589-024-01620-6 PMID: 37662341 Free PMC article. Updated. Preprint.
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Among authors: wingler lm. Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4. Epub 2021 Jun 24. Nat Chem Biol. 2021. PMID: 34168368 Free PMC article.
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Among authors: wingler lm. bioRxiv [Preprint]. 2020 Nov 11:2020.11.11.378778. doi: 10.1101/2020.11.11.378778. bioRxiv. 2020. Update in: Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4 PMID: 33200136 Free PMC article. Updated. Preprint.
Synthetic nanobodies as angiotensin receptor blockers.
McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. McMahon C, et al. Among authors: wingler lm. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20284-20291. doi: 10.1073/pnas.2009029117. Epub 2020 Aug 4. Proc Natl Acad Sci U S A. 2020. PMID: 32753386 Free PMC article.
30 results