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Page 1
Eltrombopag in chronic myelomonocytic leukemia with severe thrombocytopenia. A Groupe Francophone des Myélodysplasies (GFM) study.
Rabian F, Chevret S, Gruson B, Thépot S, Walter-Petrich A, Braun T, Vey N, Torregrosa-Diaz JM, Peterlin P, Toma A, D'Aveni M, Delaunay J, Legros L, Droin N, Chermat F, Lusina D, Adès L, Sapena R, Solary E, Fenaux P, Itzykson R. Rabian F, et al. Among authors: droin n. Leukemia. 2024 Nov;38(11):2510-2513. doi: 10.1038/s41375-024-02402-8. Epub 2024 Sep 12. Leukemia. 2024. PMID: 39266637 No abstract available.
A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner.
Ragu S, Droin N, Matos-Rodrigues G, Barascu A, Caillat S, Zarkovic G, Siberchicot C, Dardillac E, Gelot C, Guirouilh-Barbat J, Radicella JP, Ishchenko AA, Ravanat JL, Solary E, Lopez BS. Ragu S, et al. Among authors: droin n. Cell Death Differ. 2023 May;30(5):1349-1365. doi: 10.1038/s41418-023-01141-0. Epub 2023 Mar 3. Cell Death Differ. 2023. PMID: 36869180 Free PMC article.
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer.
Ma HL, Bizet M, Soares Da Costa C, Murisier F, de Bony EJ, Wang MK, Yoshimi A, Lin KT, Riching KM, Wang X, Beckman JI, Arya S, Droin N, Calonne E, Hassabi B, Zhang QY, Li A, Putmans P, Malbec L, Hubert C, Lan J, Mies F, Yang Y, Solary E, Daniels DL, Gupta YK, Deplus R, Abdel-Wahab O, Yang YG, Fuks F. Ma HL, et al. Among authors: droin n. Mol Cell. 2023 Dec 7;83(23):4239-4254.e10. doi: 10.1016/j.molcel.2023.11.003. Mol Cell. 2023. PMID: 38065062 Free PMC article.
When monoclonal gammopathy-associated chronic neutrophilic leukemia is a reactive process distinct from a clonal myeloproliferative neoplasm: Lessons from mistakes.
Willekens C, Chahine C, Dragani M, Khalife-Hachem S, Bigenwald C, Rossignol J, Castilla-Llorente C, Danu A, Michot JM, Saada V, Cotteret S, Marzac C, Renneville A, Plo I, Broutin S, Bosselut N, Cassinat B, Lazarovici J, Droin N, De Botton S. Willekens C, et al. Among authors: droin n. EJHaem. 2023 May 19;4(3):823-826. doi: 10.1002/jha2.713. eCollection 2023 Aug. EJHaem. 2023. PMID: 37601857 Free PMC article. No abstract available.
Prognostic impact of genetic abnormalities in 536 first-line chronic lymphocytic leukaemia patients without 17p deletion treated with chemoimmunotherapy in two prospective trials: Focus on IGHV-mutated subgroups (a FILO study).
Nguyen-Khac F, Baron M, Guièze R, Feugier P, Fayault A, Raynaud S, Troussard X, Droin N, Damm F, Smagghe L, Susin S, Leblond V, Dartigeas C, Van den Neste E, Leprêtre S, Bernard OA, Roos-Weil D; on behalf the FILO (French Innovative Leukaemia Organization) Group. Nguyen-Khac F, et al. Among authors: droin n. Br J Haematol. 2024 Aug;205(2):495-502. doi: 10.1111/bjh.19459. Epub 2024 Apr 23. Br J Haematol. 2024. PMID: 38654616
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis.
Basso-Valentina F, Donada A, Manchev VT, Lisetto M, Balayn N, Martin JE, Muller D, Oyarzun CPM, Duparc H, Arkoun B, Cumin A, Faivre L, Droin N, Biunno I, Pecci A, Balduini A, Debili N, Antony-Debré I, Marty C, Vainchenker W, Plo I, Favier R, Raslova H. Basso-Valentina F, et al. Among authors: droin n. Haematologica. 2023 Aug 1;108(8):2130-2145. doi: 10.3324/haematol.2022.282049. Haematologica. 2023. PMID: 36794499 Free PMC article.
Monocytes generated by interleukin-6-treated human hematopoietic stem and progenitor cells secrete calprotectin that inhibits erythropoiesis.
Marchand V, Laplane L, Valensi L, Plo I, Aglave M, Silvin A, Pasquier F, Porteu F, Vainchenker W, Selimoglu-Buet D, Droin N, Raslova H, Marcel V, Diaz JJ, Fontenay M, Solary E. Marchand V, et al. Among authors: droin n. iScience. 2024 Dec 2;28(1):111522. doi: 10.1016/j.isci.2024.111522. eCollection 2025 Jan 17. iScience. 2024. PMID: 39811665 Free PMC article.
Targeting heterochromatin eliminates chronic myelomonocytic leukemia malignant stem cells through reactivation of retroelements and immune pathways.
Hidaoui D, Porquet A, Chelbi R, Bohm M, Polyzou A, Alcazer V, Depil S, Imanci A, Morabito M, Renneville A, Selimoglu-Buet D, Thépot S, Itzykson R, Laplane L, Droin N, Trompouki E, Elvira-Matelot E, Solary E, Porteu F. Hidaoui D, et al. Among authors: droin n. Commun Biol. 2024 Nov 22;7(1):1555. doi: 10.1038/s42003-024-07214-1. Commun Biol. 2024. PMID: 39578583 Free PMC article.
CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia.
Deschamps P, Wacheux M, Gosseye A, Morabito M, Pagès A, Lyne AM, Alfaro A, Rameau P, Imanci A, Chelbi R, Marchand V, Renneville A, Patnaik MM, Lapierre V, Badaoui B, Wagner-Ballon O, Berthon C, Braun T, Willekens C, Itzykson R, Fenaux P, Thépot S, Etienne G, Elvira-Matelot E, Porteu F, Droin N, Perié L, Laplane L, Solary E, Selimoglu-Buet D. Deschamps P, et al. Among authors: droin n. J Clin Invest. 2024 Sep 17;134(22):e180738. doi: 10.1172/JCI180738. J Clin Invest. 2024. PMID: 39545419 Free PMC article.
RNA Shielding of p65 Is Required to Potentiate Oncogenic Inflammation in TET2-Mutated Clonal Hematopoiesis.
Ben-Crentsil NA, Mohammed Ismail W, Balasis ME, Newman H, Quintana A, Binder M, Kruer T, Neupane S, Ferrall-Fairbanks MC, Fernandez J, Lasho TL, Finke CM, Ibrahim ML, McGraw KL, Wysota M, Aldrich AL, Ryder CB, Letson CT, Traina J, McLemore AF, Droin N, Shastri A, Yun S, Solary E, Sallman DA, Beg AA, Ma L, Gaspar-Maia A, Patnaik MM, Padron E. Ben-Crentsil NA, et al. Among authors: droin n. Cancer Discov. 2024 Dec 2;14(12):2509-2531. doi: 10.1158/2159-8290.CD-24-0093. Cancer Discov. 2024. PMID: 39189614
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