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Page 1
Claudin 18 turns up the heat in cancer.
Zhang J, Westcott PMK. Zhang J, et al. Among authors: westcott pmk. Immunity. 2024 Jun 11;57(6):1187-1189. doi: 10.1016/j.immuni.2024.05.015. Immunity. 2024. PMID: 38865963
The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1.
Romero R, Chu T, González Robles TJ, Smith P, Xie Y, Kaur H, Yoder S, Zhao H, Mao C, Kang W, Pulina MV, Lawrence KE, Gopalan A, Zaidi S, Yoo K, Choi J, Fan N, Gerstner O, Karthaus WR, DeStanchina E, Ruggles KV, Westcott PMK, Chaligné R, Pe'er D, Sawyers CL. Romero R, et al. Among authors: westcott pmk. Nat Cancer. 2024 Nov;5(11):1641-1659. doi: 10.1038/s43018-024-00838-6. Epub 2024 Oct 11. Nat Cancer. 2024. PMID: 39394434 Free PMC article.
The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1.
Romero R, Chu T, González-Robles TJ, Smith P, Xie Y, Kaur H, Yoder S, Zhao H, Mao C, Kang W, Pulina MV, Lawrence KE, Gopalan A, Zaidi S, Yoo K, Choi J, Fan N, Gerstner O, Karthaus WR, DeStanchina E, Ruggles KV, Westcott PMK, Chaligné R, Pe'er D, Sawyers CL. Romero R, et al. Among authors: westcott pmk. bioRxiv [Preprint]. 2024 Apr 11:2024.04.09.588557. doi: 10.1101/2024.04.09.588557. bioRxiv. 2024. Update in: Nat Cancer. 2024 Nov;5(11):1641-1659. doi: 10.1038/s43018-024-00838-6 PMID: 38645223 Free PMC article. Updated. Preprint.
SOX17 enables immune evasion of early colorectal adenomas and cancers.
Goto N, Westcott PMK, Goto S, Imada S, Taylor MS, Eng G, Braverman J, Deshpande V, Jacks T, Agudo J, Yilmaz ÖH. Goto N, et al. Among authors: westcott pmk. Nature. 2024 Mar;627(8004):636-645. doi: 10.1038/s41586-024-07135-3. Epub 2024 Feb 28. Nature. 2024. PMID: 38418875
Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity.
Westcott PMK, Muyas F, Hauck H, Smith OC, Sacks NJ, Ely ZA, Jaeger AM, Rideout WM 3rd, Zhang D, Bhutkar A, Beytagh MC, Canner DA, Jaramillo GC, Bronson RT, Naranjo S, Jin A, Patten JJ, Cruz AM, Shanahan SL, Cortes-Ciriano I, Jacks T. Westcott PMK, et al. Nat Genet. 2023 Oct;55(10):1686-1695. doi: 10.1038/s41588-023-01499-4. Epub 2023 Sep 14. Nat Genet. 2023. PMID: 37709863 Free PMC article.
A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Ely ZA, Mathey-Andrews N, Naranjo S, Gould SI, Mercer KL, Newby GA, Cabana CM, Rideout WM 3rd, Jaramillo GC, Khirallah JM, Holland K, Randolph PB, Freed-Pastor WA, Davis JR, Kulstad Z, Westcott PMK, Lin L, Anzalone AV, Horton BL, Pattada NB, Shanahan SL, Ye Z, Spranger S, Xu Q, Sánchez-Rivera FJ, Liu DR, Jacks T. Ely ZA, et al. Among authors: westcott pmk. Nat Biotechnol. 2024 Mar;42(3):424-436. doi: 10.1038/s41587-023-01783-y. Epub 2023 May 11. Nat Biotechnol. 2024. PMID: 37169967 Free PMC article.
Deciphering the immunopeptidome in vivo reveals new tumour antigens.
Jaeger AM, Stopfer LE, Ahn R, Sanders EA, Sandel DA, Freed-Pastor WA, Rideout WM 3rd, Naranjo S, Fessenden T, Nguyen KB, Winter PS, Kohn RE, Westcott PMK, Schenkel JM, Shanahan SL, Shalek AK, Spranger S, White FM, Jacks T. Jaeger AM, et al. Among authors: westcott pmk. Nature. 2022 Jul;607(7917):149-155. doi: 10.1038/s41586-022-04839-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705813 Free PMC article.
24 results