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Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling.
Keles M, Grein S, Froese N, Wirth D, Trogisch FA, Wardman R, Hemanna S, Weinzierl N, Koch PS, Uhlig S, Lomada S, Dittrich GM, Szaroszyk M, Haustein R, Hegermann J, Martin-Garrido A, Bauersachs J, Frank D, Frey N, Bieback K, Cordero J, Dobreva G, Wieland T, Heineke J. Keles M, et al. Among authors: koch ps. Mol Ther Nucleic Acids. 2024 Aug 15;35(3):102306. doi: 10.1016/j.omtn.2024.102306. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39281699 Free PMC article.
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9.
Trogisch FA, Abouissa A, Keles M, Birke A, Fuhrmann M, Dittrich GM, Weinzierl N, Wink E, Cordero J, Elsherbiny A, Martin-Garrido A, Grein S, Hemanna S, Hofmann E, Nicin L, Bibli SI, Airik R, Kispert A, Kist R, Quanchao S, Kürschner SW, Winkler M, Gretz N, Mogler C, Korff T, Koch PS, Dimmeler S, Dobreva G, Heineke J. Trogisch FA, et al. Among authors: koch ps. Sci Transl Med. 2024 Feb 28;16(736):eabq4581. doi: 10.1126/scitranslmed.abq4581. Epub 2024 Feb 28. Sci Transl Med. 2024. PMID: 38416842
Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation.
Koch PS, Sandorski K, Heil J, Schmid CD, Kürschner SW, Hoffmann J, Winkler M, Staniczek T, de la Torre C, Sticht C, Schledzewski K, Taketo MM, Trogisch FA, Heineke J, Géraud C, Goerdt S, Olsavszky V. Koch PS, et al. Front Physiol. 2021 Sep 29;12:722394. doi: 10.3389/fphys.2021.722394. eCollection 2021. Front Physiol. 2021. PMID: 34658910 Free PMC article.
ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver.
Schmid CD, Olsavszky V, Reinhart M, Weyer V, Trogisch FA, Sticht C, Winkler M, Kürschner SW, Hoffmann J, Ola R, Staniczek T, Heineke J, Straub BK, Mittler J, Schledzewski K, Ten Dijke P, Richter K, Dooley S, Géraud C, Goerdt S, Koch PS. Schmid CD, et al. Among authors: koch ps. Hepatology. 2023 Apr 1;77(4):1211-1227. doi: 10.1002/hep.32641. Epub 2022 Jul 17. Hepatology. 2023. PMID: 35776660 Free PMC article.
Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling.
Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang XJ, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Koch PS, Goerdt S. Winkler M, et al. Among authors: koch ps. J Hepatol. 2021 Feb;74(2):380-393. doi: 10.1016/j.jhep.2020.08.033. Epub 2020 Sep 9. J Hepatol. 2021. PMID: 32916216 Free article.
Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling.
Wohlfeil SA, Häfele V, Dietsch B, Schledzewski K, Winkler M, Zierow J, Leibing T, Mohammadi MM, Heineke J, Sticht C, Olsavszky V, Koch PS, Géraud C, Goerdt S. Wohlfeil SA, et al. Among authors: koch ps. Cancer Res. 2019 Feb 1;79(3):598-610. doi: 10.1158/0008-5472.CAN-18-1752. Epub 2018 Dec 10. Cancer Res. 2019. PMID: 30530502
Repair of Large Defects of the Ear Helix.
Olsavszky V, Benecke J, Koch PS, Felcht M. Olsavszky V, et al. Among authors: koch ps. Dermatol Surg. 2021 Mar 1;47(3):401-403. doi: 10.1097/DSS.0000000000002328. Dermatol Surg. 2021. PMID: 32058419 No abstract available.
Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation.
Heil J, Olsavszky V, Busch K, Klapproth K, de la Torre C, Sticht C, Sandorski K, Hoffmann J, Schönhaber H, Zierow J, Winkler M, Schmid CD, Staniczek T, Daniels DE, Frayne J, Metzgeroth G, Nowak D, Schneider S, Neumaier M, Weyer V, Groden C, Gröne HJ, Richter K, Mogler C, Taketo MM, Schledzewski K, Géraud C, Goerdt S, Koch PS. Heil J, et al. Among authors: koch ps. Nat Commun. 2021 Nov 29;12(1):6963. doi: 10.1038/s41467-021-27161-3. Nat Commun. 2021. PMID: 34845225 Free PMC article.
44 results