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423 results

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Page 1
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome.
Goold HD, Kroukamp H, Erpf PE, Zhao Y, Kelso P, Calame J, Timmins JJB, Wightman ELI, Peng K, Carpenter AC, Llorente B, Hawthorne C, Clay S, van Wyk N, Daniel EL, Harrison F, Meier F, Willows RD, Cai Y, Walker RSK, Xu X, Espinosa MI, Stracquadanio G, Bader JS, Mitchell LA, Boeke JD, Williams TC, Paulsen IT, Pretorius IS. Goold HD, et al. Among authors: boeke jd. Nat Commun. 2025 Jan 20;16(1):841. doi: 10.1038/s41467-024-55318-3. Nat Commun. 2025. PMID: 39833175 Free PMC article.
Engineered transcription-associated Cas9 targeting in eukaryotic cells.
Goldberg GW, Kogenaru M, Keegan S, Haase MAB, Kagermazova L, Arias MA, Onyebeke K, Adams S, Beyer DK, Fenyö D, Noyes MB, Boeke JD. Goldberg GW, et al. Among authors: boeke jd. Nat Commun. 2024 Nov 27;15(1):10287. doi: 10.1038/s41467-024-54629-9. Nat Commun. 2024. PMID: 39604381 Free PMC article.
Enhancer activation from transposable elements in extrachromosomal DNA.
Kraft K, Murphy SE, Jones MG, Shi Q, Bhargava-Shah A, Luong C, Hung KL, He BJ, Li R, Park SK, Weiser NE, Luebeck J, Bafna V, Boeke JD, Mischel PS, Boettiger AN, Chang HY. Kraft K, et al. Among authors: boeke jd. bioRxiv [Preprint]. 2024 Sep 8:2024.09.04.611262. doi: 10.1101/2024.09.04.611262. bioRxiv. 2024. PMID: 39282372 Free PMC article. Preprint.
Cellular dynamics in pig-to-human kidney xenotransplantation.
Pan W, Zhang W, Zheng B, Camellato BR, Stern J, Lin Z, Khodadadi-Jamayran A, Kim J, Sommer P, Khalil K, Weldon E, Bai J, Zhu Y, Meyn P, Heguy A, Mangiola M, Griesemer A, Keating BJ, Montgomery RA, Xia B, Boeke JD. Pan W, et al. Among authors: boeke jd. Med. 2024 Aug 9;5(8):1016-1029.e4. doi: 10.1016/j.medj.2024.05.003. Epub 2024 May 21. Med. 2024. PMID: 38776915 Free article.
Integrative multi-omics profiling in human decedents receiving pig heart xenografts.
Schmauch E, Piening B, Mohebnasab M, Xia B, Zhu C, Stern J, Zhang W, Dowdell AK, Kim JI, Andrijevic D, Khalil K, Jaffe IS, Loza BL, Gragert L, Camellato BR, Oliveira MF, O'Brien DP, Chen HM, Weldon E, Gao H, Gandla D, Chang A, Bhatt R, Gao S, Lin X, Reddy KP, Kagermazova L, Habara AH, Widawsky S, Liang FX, Sall J, Loupy A, Heguy A, Taylor SEB, Zhu Y, Michael B, Jiang L, Jian R, Chong AS, Fairchild RL, Linna-Kuosmanen S, Kaikkonen MU, Tatapudi V, Lorber M, Ayares D, Mangiola M, Narula N, Moazami N, Pass H, Herati RS, Griesemer A, Kellis M, Snyder MP, Montgomery RA, Boeke JD, Keating BJ. Schmauch E, et al. Among authors: boeke jd. Nat Med. 2024 May;30(5):1448-1460. doi: 10.1038/s41591-024-02972-1. Epub 2024 May 17. Nat Med. 2024. PMID: 38760586
Genomic context sensitizes regulatory elements to genetic disruption.
Ordoñez R, Zhang W, Ellis G, Zhu Y, Ashe HJ, Ribeiro-Dos-Santos AM, Brosh R, Huang E, Hogan MS, Boeke JD, Maurano MT. Ordoñez R, et al. Among authors: boeke jd. Mol Cell. 2024 May 16;84(10):1842-1854.e7. doi: 10.1016/j.molcel.2024.04.013. Mol Cell. 2024. PMID: 38759624
Synthetic reversed sequences reveal default genomic states.
Camellato BR, Brosh R, Ashe HJ, Maurano MT, Boeke JD. Camellato BR, et al. Among authors: boeke jd. Nature. 2024 Apr;628(8007):373-380. doi: 10.1038/s41586-024-07128-2. Epub 2024 Mar 6. Nature. 2024. PMID: 38448583 Free PMC article.
On the genetic basis of tail-loss evolution in humans and apes.
Xia B, Zhang W, Zhao G, Zhang X, Bai J, Brosh R, Wudzinska A, Huang E, Ashe H, Ellis G, Pour M, Zhao Y, Coelho C, Zhu Y, Miller A, Dasen JS, Maurano MT, Kim SY, Boeke JD, Yanai I. Xia B, et al. Among authors: boeke jd. Nature. 2024 Feb;626(8001):1042-1048. doi: 10.1038/s41586-024-07095-8. Epub 2024 Feb 28. Nature. 2024. PMID: 38418917 Free PMC article.
423 results