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PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity.
Tang S, Kim SW, Olsen-Dufour A, Pearson T, Freaney M, Singley E, Jenkins M, Burkard NJ, Wozniak A, Parcon P, Wu S, Morse CL, Jana S, Liow JS, Zoghbi SS, Vendruscolo JCM, Vendruscolo LF, Pike VW, Koob GF, Volkow ND, Innis RB. Tang S, et al. Among authors: parcon p. Neuropsychopharmacology. 2024 Dec;50(2):444-451. doi: 10.1038/s41386-024-01988-y. Epub 2024 Sep 16. Neuropsychopharmacology. 2024. PMID: 39285225 Free PMC article.