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A naturally occurring 22-amino acid fragment of human hemoglobin A inhibits autophagy and HIV-1.
Freisem D, Rodriguez-Alfonso AA, Lawrenz J, Zhou Z, Monecke T, Preising N, Endres S, Wiese S, Ständker L, Kuan SL, Thal DR, Weil T, Niessing D, Barth H, Kirchhoff F, Harms M, Münch J, Sparrer KMJ. Freisem D, et al. Cell Mol Life Sci. 2024 Sep 17;81(1):409. doi: 10.1007/s00018-024-05447-1. Cell Mol Life Sci. 2024. PMID: 39289189 Free PMC article.
CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins.
Hoenigsperger H, Koepke L, Acharya D, Hunszinger V, Freisem D, Grenzner A, Wiese S, Kirchhoff F, Gack MU, Sparrer KMJ. Hoenigsperger H, et al. Among authors: freisem d. Autophagy. 2024 May;20(5):994-1014. doi: 10.1080/15548627.2023.2281128. Epub 2023 Nov 17. Autophagy. 2024. PMID: 37938186 Free PMC article.
Synaptic disruption and CREB-regulated transcription are restored by K+ channel blockers in ALS.
Catanese A, Rajkumar S, Sommer D, Freisem D, Wirth A, Aly A, Massa-López D, Olivieri A, Torelli F, Ioannidis V, Lipecka J, Guerrera IC, Zytnicki D, Ludolph A, Kabashi E, Mulaw MA, Roselli F, Böckers TM. Catanese A, et al. Among authors: freisem d. EMBO Mol Med. 2021 Jul 7;13(7):e13131. doi: 10.15252/emmm.202013131. Epub 2021 Jun 14. EMBO Mol Med. 2021. PMID: 34125498 Free PMC article.