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A naturally occurring 22-amino acid fragment of human hemoglobin A inhibits autophagy and HIV-1.
Freisem D, Rodriguez-Alfonso AA, Lawrenz J, Zhou Z, Monecke T, Preising N, Endres S, Wiese S, Ständker L, Kuan SL, Thal DR, Weil T, Niessing D, Barth H, Kirchhoff F, Harms M, Münch J, Sparrer KMJ. Freisem D, et al. Among authors: harms m. Cell Mol Life Sci. 2024 Sep 17;81(1):409. doi: 10.1007/s00018-024-05447-1. Cell Mol Life Sci. 2024. PMID: 39289189 Free PMC article.
Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling.
Hayn M, Blötz A, Rodríguez A, Vidal S, Preising N, Ständker L, Wiese S, Stürzel CM, Harms M, Gross R, Jung C, Kiene M, Jacob T, Pöhlmann S, Forssmann WG, Münch J, Sparrer KMJ, Seuwen K, Hahn BH, Kirchhoff F. Hayn M, et al. Among authors: harms m. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2023776118. doi: 10.1073/pnas.2023776118. Proc Natl Acad Sci U S A. 2021. PMID: 33431697 Free PMC article.
Endogenous Peptide Inhibitors of HIV Entry.
Harms M, Hayn M, Zech F, Kirchhoff F, Münch J. Harms M, et al. Adv Exp Med Biol. 2022;1366:65-85. doi: 10.1007/978-981-16-8702-0_5. Adv Exp Med Biol. 2022. PMID: 35412135
Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability.
Harms M, Haase A, Rodríguez-Alfonso A, Löffler J, Almeida-Hernández Y, Ruiz-Blanco YB, Albers D, Gilg A, von Bank F, Zech F, Groß R, Datta M, Jaikishan J, Draphoen B, Habib M, Ständker L, Wiese S, Lindén M, Winter G, Rasche V, Beer AJ, Jumaa H, Abadi AH, Kirchhoff F, Busch M, Dünker N, Sanchez-Garcia E, Münch J. Harms M, et al. J Control Release. 2024 Sep;373:583-598. doi: 10.1016/j.jconrel.2024.07.049. Epub 2024 Jul 30. J Control Release. 2024. PMID: 39047872 Free article.
Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability.
Harms M, Fabech Hansson R, Gilg A, Almeida-Hernández Y, Löffler J, Rodríguez-Alfonso A, Habib MMW, Albers D, Ahmed NS, Abadi AH, Winter G, Rasche V, Beer AJ, Weidinger G, Preising N, Ständker L, Wiese S, Sanchez-Garcia E, Zelikin AN, Münch J. Harms M, et al. J Med Chem. 2023 Nov 23;66(22):15189-15204. doi: 10.1021/acs.jmedchem.3c01128. Epub 2023 Nov 8. J Med Chem. 2023. PMID: 37940118 Free PMC article.
Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers.
Weil T, Groß R, Röcker A, Bravo-Rodriguez K, Heid C, Sowislok A, Le MH, Erwin N, Dwivedi M, Bart SM, Bates P, Wettstein L, Müller JA, Harms M, Sparrer K, Ruiz-Blanco YB, Stürzel CM, von Einem J, Lippold S, Read C, Walther P, Hebel M, Kreppel F, Klärner FG, Bitan G, Ehrmann M, Weil T, Winter R, Schrader T, Shorter J, Sanchez-Garcia E, Münch J. Weil T, et al. Among authors: harms m. J Am Chem Soc. 2020 Oct 7;142(40):17024-17038. doi: 10.1021/jacs.0c06400. Epub 2020 Sep 28. J Am Chem Soc. 2020. PMID: 32926779 Free PMC article.
644 results