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Germline variant affecting p53β isoforms predisposes to familial cancer.
Schubert SA, Ruano D, Joruiz SM, Stroosma J, Glavak N, Montali A, Pinto LM, Rodríguez-Girondo M, Barge-Schaapveld DQCM, Nielsen M, van Nesselrooij BPM, Mensenkamp AR, van Leerdam ME, Sharp TH, Morreau H, Bourdon JC, de Miranda NFCC, van Wezel T. Schubert SA, et al. Among authors: bourdon jc. Nat Commun. 2024 Sep 18;15(1):8208. doi: 10.1038/s41467-024-52551-8. Nat Commun. 2024. PMID: 39294166 Free PMC article.
p53 Isoforms: Key Regulators of the Cell Fate Decision.
Joruiz SM, Bourdon JC. Joruiz SM, et al. Among authors: bourdon jc. Cold Spring Harb Perspect Med. 2016 Aug 1;6(8):a026039. doi: 10.1101/cshperspect.a026039. Cold Spring Harb Perspect Med. 2016. PMID: 26801896 Free PMC article. Review.
TP53 drives invasion through expression of its Δ133p53β variant.
Gadea G, Arsic N, Fernandes K, Diot A, Joruiz SM, Abdallah S, Meuray V, Vinot S, Anguille C, Remenyi J, Khoury MP, Quinlan PR, Purdie CA, Jordan LB, Fuller-Pace FV, de Toledo M, Cren M, Thompson AM, Bourdon JC, Roux P. Gadea G, et al. Among authors: bourdon jc. Elife. 2016 Sep 15;5:e14734. doi: 10.7554/eLife.14734. Elife. 2016. PMID: 27630122 Free PMC article.
p53 isoforms can regulate p53 transcriptional activity.
Bourdon JC, Fernandes K, Murray-Zmijewski F, Liu G, Diot A, Xirodimas DP, Saville MK, Lane DP. Bourdon JC, et al. Genes Dev. 2005 Sep 15;19(18):2122-37. doi: 10.1101/gad.1339905. Epub 2005 Aug 30. Genes Dev. 2005. PMID: 16131611 Free PMC article.
Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.
Arsic N, Slatter T, Gadea G, Villain E, Fournet A, Kazantseva M, Allemand F, Sibille N, Seveno M, de Rossi S, Mehta S, Urbach S, Bourdon JC, Bernado P, Kajava AV, Braithwaite A, Roux P. Arsic N, et al. Among authors: bourdon jc. Nat Commun. 2021 Sep 15;12(1):5463. doi: 10.1038/s41467-021-25550-2. Nat Commun. 2021. PMID: 34526502 Free PMC article.
The isoforms of the p53 protein.
Khoury MP, Bourdon JC. Khoury MP, et al. Among authors: bourdon jc. Cold Spring Harb Perspect Biol. 2010 Mar;2(3):a000927. doi: 10.1101/cshperspect.a000927. Cold Spring Harb Perspect Biol. 2010. PMID: 20300206 Free PMC article. Review.
p53 Family isoforms.
Bourdon JC. Bourdon JC. Curr Pharm Biotechnol. 2007 Dec;8(6):332-6. doi: 10.2174/138920107783018444. Curr Pharm Biotechnol. 2007. PMID: 18289041 Free PMC article. Review.
94 results