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Combination of a mitogen-activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion-based residual disease and prevents re-expansion of FLT3-ITD acute myeloid leukaemia.
Zabkiewicz J, Lazenby M, Edwards G, Bygrave CA, Omidvar N, Zhuang L, Knapper S, Guy C, Hills RK, Burnett AK, Alvares CL. Zabkiewicz J, et al. Among authors: alvares cl. Br J Haematol. 2020 Oct;191(2):231-242. doi: 10.1111/bjh.16665. Epub 2020 May 11. Br J Haematol. 2020. PMID: 32394450 Free article.
The combination of cyclophosphomide, thalidomide and dexamethasone is an effective alternative to cyclophosphamide - vincristine - doxorubicin - methylprednisolone as induction chemotherapy prior to autologous transplantation for multiple myeloma: a case-matched analysis.
Wu P, Davies FE, Horton C, Jenner MW, Krishnan B, Alvares CL, Saso R, McCormack R, Dines S, Treleaven JG, Potter MN, Ethell ME, Morgan GJ. Wu P, et al. Among authors: alvares cl. Leuk Lymphoma. 2006 Nov;47(11):2335-8. doi: 10.1080/10428190600821955. Leuk Lymphoma. 2006. PMID: 17107906
MHC-related protein 1-restricted recognition of cancer via a semi-invariant TCR-α chain.
Dolton G, Thomas H, Tan LR, Rius Rafael C, Doetsch S, Ionescu GA, Cardo LF, Crowther MD, Behiry E, Morin T, Caillaud ME, Srai D, Parolini L, Hasan MS, Fuller A, Topley K, Wall A, Hopkins JR, Omidvar N, Alvares C, Zabkiewicz J, Frater J, Szomolay B, Sewell AK. Dolton G, et al. Among authors: alvares c. J Clin Invest. 2025 Jan 2;135(1):e181895. doi: 10.1172/JCI181895. J Clin Invest. 2025. PMID: 39744940 Free PMC article.
Inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells.
Hieber C, Mustafa AM, Neuroth S, Henninger S, Wollscheid HP, Zabkiewicz J, Lazenby M, Alvares C, Mahboobi S, Butter F, Brenner W, Bros M, Krämer OH. Hieber C, et al. Among authors: alvares c. Biomed Pharmacother. 2024 Aug;177:117076. doi: 10.1016/j.biopha.2024.117076. Epub 2024 Jul 5. Biomed Pharmacother. 2024. PMID: 38971011 Free article.
56 results