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Page 1
Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia.
Jin Q, Harris E, Myers JA, Mehmood R, Cotton A, Shirnekhi HK, Baggett DW, Wen JQ, Schild AB, Bhansali RS, Klein J, Narina S, Pieters T, Yoshimi A, Pruett-Miller SM, Kriwacki R, Abdel-Wahab O, Malinge S, Ntziachristos P, Obeng EA, Crispino JD. Jin Q, et al. Among authors: crispino jd. Blood. 2024 Dec 5;144(23):2417-2431. doi: 10.1182/blood.2024024281. Blood. 2024. PMID: 39316649 Free PMC article.
Down syndrome and leukemia: from basic mechanisms to clinical advances.
Baruchel A, Bourquin JP, Crispino J, Cuartero S, Hasle H, Hitzler J, Klusmann JH, Izraeli S, Lane AA, Malinge S, Rabin KR, Roberts I, Ryeom S, Tasian SK, Wagenblast E. Baruchel A, et al. Haematologica. 2023 Oct 1;108(10):2570-2581. doi: 10.3324/haematol.2023.283225. Haematologica. 2023. PMID: 37439336 Free PMC article. Review.
Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia.
Carey-Smith SL, Simad MH, Panchal K, Aya-Bonilla C, Smolders H, Lin S, Armitage JD, Nguyen VT, Bentley K, Ford J, Singh S, Oommen J, Laurent AP, Mercher T, Crispino JD, Montgomery AP, Kassiou M, Besson T, Deau E, Meijer L, Cheung LC, Kotecha RS, Malinge S. Carey-Smith SL, et al. Among authors: crispino jd. Haematologica. 2024 Jul 1;109(7):2309-2315. doi: 10.3324/haematol.2023.284271. Haematologica. 2024. PMID: 38426275 Free PMC article. No abstract available.
Malignant progression of preleukemic disorders.
Hall T, Gurbuxani S, Crispino JD. Hall T, et al. Among authors: crispino jd. Blood. 2024 May 30;143(22):2245-2255. doi: 10.1182/blood.2023020817. Blood. 2024. PMID: 38498034 Review.
The developmental clock: where art and science meet.
Crispino JD. Crispino JD. Exp Hematol. 2024 Dec 5;142:104695. doi: 10.1016/j.exphem.2024.104695. Online ahead of print. Exp Hematol. 2024. PMID: 39645186 No abstract available.
Building Synthetic Biosensors Using Red Blood Cell Proteins.
Dolberg TB, Gunnels TF, Ling T, Sarnese KA, Crispino JD, Leonard JN. Dolberg TB, et al. Among authors: crispino jd. ACS Synth Biol. 2024 Apr 19;13(4):1273-1289. doi: 10.1021/acssynbio.3c00754. Epub 2024 Mar 27. ACS Synth Biol. 2024. PMID: 38536408
Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A.
Brierley CK, Yip BH, Orlando G, Goyal H, Wen S, Wen J, Levine MF, Jakobsdottir GM, Rodriguez-Meira A, Adamo A, Bashton M, Hamblin A, Clark SA, O'Sullivan J, Murphy L, Olijnik AA, Cotton A, Narina S, Pruett-Miller SM, Enshaei A, Harrison C, Drummond M, Knapper S, Tefferi A, Antony-Debré I, Thongjuea S, Wedge DC, Constantinescu S, Papaemmanuil E, Psaila B, Crispino JD, Mead AJ. Brierley CK, et al. Among authors: crispino jd. bioRxiv [Preprint]. 2023 Dec 10:2023.12.08.570880. doi: 10.1101/2023.12.08.570880. bioRxiv. 2023. PMID: 38106192 Free PMC article. Preprint.
162 results