Treacy JW - Search Results

1

WDR5 Binding to Histone Serotonylation Is Driven by an Edge-Face Aromatic Interaction with Unexpected Electrostatic Effects.

Travis CR, Henriksen HC, Wilkinson JR, Schomburg NK, Treacy JW, Kean KM, Houk KN, Waters ML. Travis CR, et al. Among authors: treacy jw. J Am Chem Soc. 2024 Oct 9;146(40):27451-27459. doi: 10.1021/jacs.4c07277. Epub 2024 Sep 25. J Am Chem Soc. 2024. PMID: 39321462

2

Intramolecular N-H⋅⋅⋅F Hydrogen Bonding Interaction in a Series of 4-Anilino-5-Fluoroquinazolines: Experimental and Theoretical Characterization of Electronic and Conformational Effects.

Urner LM, Young Lee G, Treacy JW, Turlik A, Khan SI, Houk KN, Jung ME. Urner LM, et al. Among authors: treacy jw. Chemistry. 2022 Jan 10;28(2):e202103135. doi: 10.1002/chem.202103135. Epub 2021 Dec 4. Chemistry. 2022. PMID: 34767667 Free PMC article.

3

Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding.

Kean KM, Baril SA, Lamb KN, Dishman SN, Treacy JW, Houk KN, Brustad EM, James LI, Waters ML. Kean KM, et al. Among authors: treacy jw. J Med Chem. 2022 Feb 10;65(3):2646-2655. doi: 10.1021/acs.jmedchem.1c02049. Epub 2022 Jan 11. J Med Chem. 2022. PMID: 35014255 Free PMC article.

4

Comparative Analysis of Sulfonium-π, Ammonium-π, and Sulfur-π Interactions and Relevance to SAM-Dependent Methyltransferases.

Albanese KI, Leaver-Fay A, Treacy JW, Park R, Houk KN, Kuhlman B, Waters ML. Albanese KI, et al. Among authors: treacy jw. J Am Chem Soc. 2022 Feb 16;144(6):2535-2545. doi: 10.1021/jacs.1c09902. Epub 2022 Feb 2. J Am Chem Soc. 2022. PMID: 35108000 Free PMC article.

5

Self-Immolative Hydroxybenzylamine Linkers for Traceless Protein Modification.

Rose DA, Treacy JW, Yang ZJ, Ko JH, Houk KN, Maynard HD. Rose DA, et al. Among authors: treacy jw. J Am Chem Soc. 2022 Apr 6;144(13):6050-6058. doi: 10.1021/jacs.2c01136. Epub 2022 Mar 24. J Am Chem Soc. 2022. PMID: 35321547

6

Arene C-H borylation strategy enabled by a non-classical boron cluster-based electrophile.

Kim S, Treacy JW, Nelson YA, Gonzalez JAM, Gembicky M, Houk KN, Spokoyny AM. Kim S, et al. Among authors: treacy jw. Nat Commun. 2023 Mar 25;14(1):1671. doi: 10.1038/s41467-023-37258-6. Nat Commun. 2023. PMID: 36966132 Free PMC article.

7

Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands.

Travis CR, Kean KM, Albanese KI, Henriksen HC, Treacy JW, Chao EY, Houk KN, Waters ML. Travis CR, et al. Among authors: treacy jw. J Am Chem Soc. 2024 Feb 7;146(5):3086-3093. doi: 10.1021/jacs.3c10031. Epub 2024 Jan 24. J Am Chem Soc. 2024. PMID: 38266163

8

Ultrafast Au(III)-Mediated Arylation of Cysteine.

Doud EA, Tilden JAR, Treacy JW, Chao EY, Montgomery HR, Kunkel GE, Olivares EJ, Adhami N, Kerr TA, Chen Y, Rheingold AL, Loo JA, Frost CG, Houk KN, Maynard HD, Spokoyny AM. Doud EA, et al. Among authors: treacy jw. J Am Chem Soc. 2024 May 8;146(18):12365-12374. doi: 10.1021/jacs.3c12170. Epub 2024 Apr 24. J Am Chem Soc. 2024. PMID: 38656163

9

Comparison of Cyclic and Linear PEG Conjugates.

Kunkel GE, Zhou Q, Treacy JW, Montgomery HR, Salas-Ambrosio P, Ready AD, Spokoyny AM, Houk KN, Maynard HD. Kunkel GE, et al. Among authors: treacy jw. Bioconjug Chem. 2024 Jun 19;35(6):744-749. doi: 10.1021/acs.bioconjchem.4c00202. Epub 2024 May 29. Bioconjug Chem. 2024. PMID: 38809040 Free PMC article.

10

Controlling rates and reversibilities of elimination reactions of hydroxybenzylammoniums by tuning dearomatization energies.

Fu Z, Treacy JW, Hosier BM, Houk KN, Maynard HD. Fu Z, et al. Among authors: treacy jw. Chem Sci. 2024 Jun 7;15(27):10448-10454. doi: 10.1039/d4sc02985b. eCollection 2024 Jul 10. Chem Sci. 2024. PMID: 38994402 Free PMC article.

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