Waters ML - Search Results

1

WDR5 Binding to Histone Serotonylation Is Driven by an Edge-Face Aromatic Interaction with Unexpected Electrostatic Effects.

Travis CR, Henriksen HC, Wilkinson JR, Schomburg NK, Treacy JW, Kean KM, Houk KN, Waters ML. Travis CR, et al. Among authors: waters ml. J Am Chem Soc. 2024 Oct 9;146(40):27451-27459. doi: 10.1021/jacs.4c07277. Epub 2024 Sep 25. J Am Chem Soc. 2024. PMID: 39321462

2

More Than π-π-π Stacking: Contribution of Amide-π and CH-π Interactions to Crotonyllysine Binding by the AF9 YEATS Domain.

Krone MW, Travis CR, Lee GY, Eckvahl HJ, Houk KN, Waters ML. Krone MW, et al. Among authors: waters ml. J Am Chem Soc. 2020 Oct 7;142(40):17048-17056. doi: 10.1021/jacs.0c06568. Epub 2020 Sep 23. J Am Chem Soc. 2020. PMID: 32926780 Free PMC article.

3

Comparative Analysis of Sulfonium-π, Ammonium-π, and Sulfur-π Interactions and Relevance to SAM-Dependent Methyltransferases.

Albanese KI, Leaver-Fay A, Treacy JW, Park R, Houk KN, Kuhlman B, Waters ML. Albanese KI, et al. Among authors: waters ml. J Am Chem Soc. 2022 Feb 16;144(6):2535-2545. doi: 10.1021/jacs.1c09902. Epub 2022 Feb 2. J Am Chem Soc. 2022. PMID: 35108000 Free PMC article.

4

Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands.

Travis CR, Kean KM, Albanese KI, Henriksen HC, Treacy JW, Chao EY, Houk KN, Waters ML. Travis CR, et al. Among authors: waters ml. J Am Chem Soc. 2024 Feb 7;146(5):3086-3093. doi: 10.1021/jacs.3c10031. Epub 2024 Jan 24. J Am Chem Soc. 2024. PMID: 38266163

5

Contribution of Electrostatic CH₃-π Interactions to Recognition of Histone Asymmetric Dimethylarginine by the SPIN1 Triple Tudor Domain.

Travis CR, Dumais RG, Treacy JW, Kean KM, Houk KN, Waters ML. Travis CR, et al. Among authors: waters ml. J Am Chem Soc. 2024 Jul 31;146(30):20678-20684. doi: 10.1021/jacs.4c03463. Epub 2024 Jul 18. J Am Chem Soc. 2024. PMID: 39023428

6

Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.

Baril SA, Koenig AL, Krone MW, Albanese KI, He CQ, Lee GY, Houk KN, Waters ML, Brustad EM. Baril SA, et al. Among authors: waters ml. J Am Chem Soc. 2017 Dec 6;139(48):17253-17256. doi: 10.1021/jacs.7b09223. Epub 2017 Nov 20. J Am Chem Soc. 2017. PMID: 29111699 Free PMC article.

7

Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding.

Kean KM, Baril SA, Lamb KN, Dishman SN, Treacy JW, Houk KN, Brustad EM, James LI, Waters ML. Kean KM, et al. Among authors: waters ml. J Med Chem. 2022 Feb 10;65(3):2646-2655. doi: 10.1021/acs.jmedchem.1c02049. Epub 2022 Jan 11. J Med Chem. 2022. PMID: 35014255 Free PMC article.

8

Evaluation of acyllysine isostere interactions with the aromatic pocket of the AF9 YEATS domain.

Travis CR, Francis DY, Williams DC Jr, Waters ML. Travis CR, et al. Among authors: waters ml. Protein Sci. 2023 Jan;32(1):e4533. doi: 10.1002/pro.4533. Protein Sci. 2023. PMID: 36482045 Free PMC article.

9

Mismatched covalent and noncovalent templating leads to large coiled coil-templated macrocycles.

Stingley KJ, Carpenter BA, Kean KM, Waters ML. Stingley KJ, et al. Among authors: waters ml. Chem Sci. 2023 Apr 3;14(18):4935-4944. doi: 10.1039/d3sc00231d. eCollection 2023 May 10. Chem Sci. 2023. PMID: 37181761 Free PMC article.

10

Stimulus-Induced Relief of Intentionally Incorporated Frustration Drives Refolding of a Water-Soluble Biomimetic Foldamer.

Henriksen HC, Sowers AJ, Travis CR, Vulpis TD, Cope TA, Ouslander SK, Russell AF, Gagné MR, Pophristic V, Liu Z, Waters ML. Henriksen HC, et al. Among authors: waters ml. J Am Chem Soc. 2023 Dec 20;145(50):27672-27679. doi: 10.1021/jacs.3c09883. Epub 2023 Dec 6. J Am Chem Soc. 2023. PMID: 38054648 Free PMC article.

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