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A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development.
Fan AT, Gadbois GE, Huang HT, Jiang J, Sigua LH, Smith ER, Wu S, Dunne-Dombrink K, Goyal P, Tao AJ, Sellers W, Fischer ES, Donovan KA, Ferguson FM. Fan AT, et al. Among authors: ferguson fm. bioRxiv [Preprint]. 2024 Sep 21:2024.09.17.612508. doi: 10.1101/2024.09.17.612508. bioRxiv. 2024. Update in: Angew Chem Int Ed Engl. 2024 Nov 27:e202417272. doi: 10.1002/anie.202417272 PMID: 39345570 Free PMC article. Updated. Preprint.
Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development.
Donovan KA, Ferguson FM, Bushman JW, Eleuteri NA, Bhunia D, Ryu S, Tan L, Shi K, Yue H, Liu X, Dobrovolsky D, Jiang B, Wang J, Hao M, You I, Teng M, Liang Y, Hatcher J, Li Z, Manz TD, Groendyke B, Hu W, Nam Y, Sengupta S, Cho H, Shin I, Agius MP, Ghobrial IM, Ma MW, Che J, Buhrlage SJ, Sim T, Gray NS, Fischer ES. Donovan KA, et al. Among authors: ferguson fm. Cell. 2020 Dec 10;183(6):1714-1731.e10. doi: 10.1016/j.cell.2020.10.038. Epub 2020 Dec 3. Cell. 2020. PMID: 33275901 Free PMC article.
ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC.
Tran NL, Jiang J, Ma M, Gadbois GE, Gulay KCM, Verano A, Zhou H, Huang CT, Scott DA, Bang AG, Tiriac H, Lowy AM, Wang ES, Ferguson FM. Tran NL, et al. Among authors: ferguson fm. bioRxiv [Preprint]. 2024 May 21:2024.05.19.594824. doi: 10.1101/2024.05.19.594824. bioRxiv. 2024. PMID: 38826238 Free PMC article. Preprint.
A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development.
Fan AT, Gadbois GE, Huang HT, Chaudhry C, Jiang J, Sigua LH, Smith ER, Wu S, Poirier GJ, Dunne-Dombrink K, Goyal P, Tao AJ, Sellers WR, Fischer ES, Donovan KA, Ferguson FM. Fan AT, et al. Among authors: ferguson fm. Angew Chem Int Ed Engl. 2024 Nov 27:e202417272. doi: 10.1002/anie.202417272. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39602499
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma.
Seong BKA, Dharia NV, Lin S, Donovan KA, Chong S, Robichaud A, Conway A, Hamze A, Ross L, Alexe G, Adane B, Nabet B, Ferguson FM, Stolte B, Wang EJ, Sun J, Darzacq X, Piccioni F, Gray NS, Fischer ES, Stegmaier K. Seong BKA, et al. Among authors: ferguson fm. Cancer Cell. 2021 Sep 13;39(9):1262-1278.e7. doi: 10.1016/j.ccell.2021.07.003. Epub 2021 Jul 29. Cancer Cell. 2021. PMID: 34329586 Free PMC article.
45 results