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Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors.
Kuhn B, Ritter M, Hornsperger B, Bell C, Kocer B, Rombach D, Lutz MDR, Gobbi L, Kuratli M, Bartelmus C, Bürkler M, Koller R, Tosatti P, Ruf I, Guerard M, Pavlovic A, Stephanus J, O'Hara F, Wetzl D, Saal W, Stihle M, Roth D, Hug M, Huber S, Heer D, Kroll C, Topp A, Schneider M, Gertsch J, Glasmacher S, van der Stelt M, Martella A, Wittwer MB, Collin L, Benz J, Richter H, Grether U. Kuhn B, et al. Among authors: roth d. J Med Chem. 2024 Oct 24;67(20):18448-18464. doi: 10.1021/acs.jmedchem.4c01769. Epub 2024 Oct 3. J Med Chem. 2024. PMID: 39360636
Tyramine fragment binding to BACE-1.
Kuglstatter A, Stahl M, Peters JU, Huber W, Stihle M, Schlatter D, Benz J, Ruf A, Roth D, Enderle T, Hennig M. Kuglstatter A, et al. Among authors: roth d. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1304-7. doi: 10.1016/j.bmcl.2008.01.032. Epub 2008 Jan 11. Bioorg Med Chem Lett. 2008. PMID: 18226904
E-cigarette-induced changes in cell stress and mitochondrial function.
Chitteti R, Zuniga Hertz JP, Masso-Silva JA, Shin J, Niesman I, Bojanowski CM, Kumar AJ, Hepokoski M, Crotty Alexander LE, Patel HH, Roth DM. Chitteti R, et al. Among authors: roth dm. Free Radic Biol Med. 2025 Jan 3:S0891-5849(25)00004-8. doi: 10.1016/j.freeradbiomed.2025.01.004. Online ahead of print. Free Radic Biol Med. 2025. PMID: 39756490
1,935 results