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The common VTE-protective G haplotype of F5 increases factor V-short, TFPI function, and risk of bleeding.
Sims MC, Gierula M, Stephens JC, Tokolyi A, Stefanucci L, Persyn E, Sun L, Collins JH, Davenport EE, Di Angelantonio E, Downes K, Inouye M, Paul DS, Thomas W, Tolios A, Ouwehand WH, Gleadall NS, Crawley JTB, Butterworth AS, Frontini M, Ahnström J. Sims MC, et al. Among authors: thomas w. Blood Adv. 2025 Jan 14;9(1):132-142. doi: 10.1182/bloodadvances.2024014020. Blood Adv. 2025. PMID: 39365993
Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders.
Downes K, Megy K, Duarte D, Vries M, Gebhart J, Hofer S, Shamardina O, Deevi SVV, Stephens J, Mapeta R, Tuna S, Al Hasso N, Besser MW, Cooper N, Daugherty L, Gleadall N, Greene D, Haimel M, Martin H, Papadia S, Revel-Vilk S, Sivapalaratnam S, Symington E, Thomas W, Thys C, Tolios A, Penkett CJ; NIHR BioResource; Ouwehand WH, Abbs S, Laffan MA, Turro E, Simeoni I, Mumford AD, Henskens YMC, Pabinger I, Gomez K, Freson K. Downes K, et al. Among authors: thomas w. Blood. 2019 Dec 5;134(23):2082-2091. doi: 10.1182/blood.2018891192. Blood. 2019. PMID: 31064749 Free PMC article.
Characterization of a large cohort of patients with unclassified bleeding disorder; clinical features, management of haemostatic challenges and use of global haemostatic assessment with proposed recommendations for diagnosis and treatment.
MacDonald S, Wright A, Beuche F, Downes K, Besser M, Symington E, Kelly A, Thomas W. MacDonald S, et al. Among authors: thomas w. Int J Lab Hematol. 2020 Apr;42(2):116-125. doi: 10.1111/ijlh.13124. Epub 2019 Nov 20. Int J Lab Hematol. 2020. PMID: 31747136 Clinical Trial.
Investigation of patients with unclassified bleeding disorder and abnormal thrombin generation for physiological coagulation inhibitors reveals multiple abnormalities and a subset of patients with increased tissue factor pathway inhibitor activity.
MacDonald S, White D, Langdown J, Downes K, Thomas W. MacDonald S, et al. Among authors: thomas w. Int J Lab Hematol. 2020 Jun;42(3):246-255. doi: 10.1111/ijlh.13155. Epub 2020 Jan 31. Int J Lab Hematol. 2020. PMID: 32003946 Clinical Trial.
Presenting ADAMTS13 antibody and antigen levels predict prognosis in immune-mediated thrombotic thrombocytopenic purpura.
Alwan F, Vendramin C, Vanhoorelbeke K, Langley K, McDonald V, Austin S, Clark A, Lester W, Gooding R, Biss T, Dutt T, Cooper N, Chapman O, Cranfield T, Douglas K, Watson HG, van Veen JJ, Sibson K, Thomas W, Manson L, Hill QA, Benjamin S, Ellis D, Westwood JP, Thomas M, Scully M. Alwan F, et al. Among authors: thomas w, thomas m. Blood. 2017 Jul 27;130(4):466-471. doi: 10.1182/blood-2016-12-758656. Epub 2017 Jun 2. Blood. 2017. PMID: 28576877 Free article. Clinical Trial.
Characterization and treatment of congenital thrombotic thrombocytopenic purpura.
Alwan F, Vendramin C, Liesner R, Clark A, Lester W, Dutt T, Thomas W, Gooding R, Biss T, Watson HG, Cooper N, Rayment R, Cranfield T, van Veen JJ, Hill QA, Davis S, Motwani J, Bhatnagar N, Priddee N, David M, Crowley MP, Alamelu J, Lyall H, Westwood JP, Thomas M, Scully M. Alwan F, et al. Among authors: thomas w, thomas m. Blood. 2019 Apr 11;133(15):1644-1651. doi: 10.1182/blood-2018-11-884700. Epub 2019 Feb 15. Blood. 2019. PMID: 30770395 Free article. Review.
Real-world experience with caplacizumab in the management of acute TTP.
Dutt T, Shaw RJ, Stubbs M, Yong J, Bailiff B, Cranfield T, Crowley MP, Desborough M, Eyre TA, Gooding R, Grainger J, Hanley J, Haughton J, Hermans J, Hill Q, Humphrey L, Lowe G, Lyall H, Mohsin M, Nicolson PLR, Priddee N, Rampotas A, Rayment R, Rhodes S, Taylor A, Thomas W, Tomkins O, Van Veen JJ, Lane S, Toh CH, Scully M. Dutt T, et al. Among authors: thomas w. Blood. 2021 Apr 1;137(13):1731-1740. doi: 10.1182/blood.2020007599. Blood. 2021. PMID: 33150355 Free article.
2,553 results