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Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection.
Kamel W, Noerenberg M, Cerikan B, Chen H, Järvelin AI, Kammoun M, Lee JY, Shuai N, Garcia-Moreno M, Andrejeva A, Deery MJ, Johnson N, Neufeldt CJ, Cortese M, Knight ML, Lilley KS, Martinez J, Davis I, Bartenschlager R, Mohammed S, Castello A. Kamel W, et al. Among authors: castello a. Mol Cell. 2021 Jul 1;81(13):2851-2867.e7. doi: 10.1016/j.molcel.2021.05.023. Epub 2021 May 24. Mol Cell. 2021. PMID: 34118193 Free PMC article.
Uncovering viral RNA-host cell interactions on a proteome-wide scale.
Iselin L, Palmalux N, Kamel W, Simmonds P, Mohammed S, Castello A. Iselin L, et al. Among authors: castello a. Trends Biochem Sci. 2022 Jan;47(1):23-38. doi: 10.1016/j.tibs.2021.08.002. Epub 2021 Sep 9. Trends Biochem Sci. 2022. PMID: 34509361 Free PMC article. Review.
The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
Álvarez L, Haubrich K, Iselin L, Gillioz L, Ruscica V, Lapouge K, Augsten S, Huppertz I, Choudhury NR, Simon B, Masiewicz P, Lethier M, Cusack S, Rittinger K, Gabel F, Leitner A, Michlewski G, Hentze MW, Allain FHT, Castello A, Hennig J. Álvarez L, et al. Among authors: castello a. Nat Commun. 2024 Oct 1;15(1):8485. doi: 10.1038/s41467-024-52918-x. Nat Commun. 2024. PMID: 39353916 Free PMC article.
Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences.
Lee JY, Wing PAC, Gala DS, Noerenberg M, Järvelin AI, Titlow J, Zhuang X, Palmalux N, Iselin L, Thompson MK, Parton RM, Prange-Barczynska M, Wainman A, Salguero FJ, Bishop T, Agranoff D, James W, Castello A, McKeating JA, Davis I. Lee JY, et al. Among authors: castello a. Elife. 2022 Jan 20;11:e74153. doi: 10.7554/eLife.74153. Elife. 2022. PMID: 35049501 Free PMC article.
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection.
Garcia-Moreno M, Noerenberg M, Ni S, Järvelin AI, González-Almela E, Lenz CE, Bach-Pages M, Cox V, Avolio R, Davis T, Hester S, Sohier TJM, Li B, Heikel G, Michlewski G, Sanz MA, Carrasco L, Ricci EP, Pelechano V, Davis I, Fischer B, Mohammed S, Castello A. Garcia-Moreno M, et al. Among authors: castello a. Mol Cell. 2019 Apr 4;74(1):196-211.e11. doi: 10.1016/j.molcel.2019.01.017. Epub 2019 Feb 21. Mol Cell. 2019. PMID: 30799147 Free PMC article.
452 results