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CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13.
Tien JC, Luo J, Chang Y, Zhang Y, Cheng Y, Wang X, Yang J, Mannan R, Mahapatra S, Shah P, Wang XM, Todd AJ, Eyunni S, Cheng C, Rebernick RJ, Xiao L, Bao Y, Neiswender J, Brough R, Pettitt SJ, Cao X, Miner SJ, Zhou L, Wu YM, Labanca E, Wang Y, Parolia A, Cieslik M, Robinson DR, Wang Z, Feng FY, Chou J, Lord CJ, Ding K, Chinnaiyan AM. Tien JC, et al. Among authors: todd aj. Cell Rep Med. 2024 Oct 15;5(10):101758. doi: 10.1016/j.xcrm.2024.101758. Epub 2024 Oct 4. Cell Rep Med. 2024. PMID: 39368479 Free PMC article.
CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality.
Tien JC, Chang Y, Zhang Y, Chou J, Cheng Y, Wang X, Yang J, Mannan R, Shah P, Wang XM, Todd AJ, Eyunni S, Cheng C, Rebernick RJ, Xiao L, Bao Y, Neiswender J, Brough R, Pettitt SJ, Cao X, Miner SJ, Zhou L, Wu YM, Labanca E, Wang Y, Parolia A, Cieslik M, Robinson DR, Wang Z, Feng FY, Lord CJ, Ding K, Chinnaiyan AM. Tien JC, et al. Among authors: todd aj. bioRxiv [Preprint]. 2024 Mar 21:2024.03.20.585990. doi: 10.1101/2024.03.20.585990. bioRxiv. 2024. Update in: Cell Rep Med. 2024 Oct 15;5(10):101758. doi: 10.1016/j.xcrm.2024.101758 PMID: 38562774 Free PMC article. Updated. Preprint.
Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons.
Bell AM, Utting C, Dickie AC, Kucharczyk MW, Quillet R, Gutierrez-Mecinas M, Razlan ANB, Cooper AH, Lan Y, Hachisuka J, Weir GA, Bannister K, Watanabe M, Kania A, Hoon MA, Macaulay IC, Denk F, Todd AJ. Bell AM, et al. Among authors: todd aj. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2314213121. doi: 10.1073/pnas.2314213121. Epub 2024 May 28. Proc Natl Acad Sci U S A. 2024. PMID: 38805282 Free PMC article.
Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons.
Bell AM, Utting C, Dickie AC, Kucharczyk MW, Quillet R, Gutierrez-Mecinas M, Razlan ANB, Cooper AH, Lan Y, Hachisuka J, Weir GA, Bannister K, Watanabe M, Kania A, Hoon MA, Macaulay IC, Denk F, Todd AJ. Bell AM, et al. Among authors: todd aj. bioRxiv [Preprint]. 2023 Sep 2:2023.08.20.553715. doi: 10.1101/2023.08.20.553715. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2314213121. doi: 10.1073/pnas.2314213121 PMID: 37786726 Free PMC article. Updated. Preprint.
Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord.
Davis OC, Dickie AC, Mustapa MB, Boyle KA, Browne TJ, Gradwell MA, Smith KM, Polgár E, Bell AM, Kókai É, Watanabe M, Wildner H, Zeilhofer HU, Ginty DD, Callister RJ, Graham BA, Todd AJ, Hughes DI. Davis OC, et al. Among authors: todd aj. Sci Rep. 2023 Jul 18;13(1):11561. doi: 10.1038/s41598-023-38605-9. Sci Rep. 2023. PMID: 37464016 Free PMC article.
Calretinin-expressing islet cells: a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord.
Davis OC, Dickie AC, Mustapa MB, Boyle KA, Browne TJ, Gradwell MA, Smith KM, Polgár E, Bell AM, Kókai É, Watanabe M, Wildner H, Zeilhofer HU, Ginty DD, Callister RJ, Graham BA, Todd AJ, Hughes DI. Davis OC, et al. Among authors: todd aj. bioRxiv [Preprint]. 2023 Jun 5:2023.06.01.543241. doi: 10.1101/2023.06.01.543241. bioRxiv. 2023. Update in: Sci Rep. 2023 Jul 18;13(1):11561. doi: 10.1038/s41598-023-38605-9 PMID: 37333120 Free PMC article. Updated. Preprint.
163 results