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Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer's disease continuum.
Wen J, Yang Z, Nasrallah IM, Cui Y, Erus G, Srinivasan D, Abdulkadir A, Mamourian E, Hwang G, Singh A, Bergman M, Bao J, Varol E, Zhou Z, Boquet-Pujadas A, Chen J, Toga AW, Saykin AJ, Hohman TJ, Thompson PM, Villeneuve S, Gollub R, Sotiras A, Wittfeld K, Grabe HJ, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Benzinger TL, Heckbert SR, Austin TR, Launer LJ, Espeland M, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Resnick SM, Ferrucci L, Fan Y, Habes M, Wolk D, Shen L, Shou H, Davatzikos C. Wen J, et al. Among authors: cui y. Transl Psychiatry. 2024 Oct 5;14(1):420. doi: 10.1038/s41398-024-03121-5. Transl Psychiatry. 2024. PMID: 39368996 Free PMC article.
A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.
Yang Z, Nasrallah IM, Shou H, Wen J, Doshi J, Habes M, Erus G, Abdulkadir A, Resnick SM, Albert MS, Maruff P, Fripp J, Morris JC, Wolk DA, Davatzikos C; iSTAGING Consortium; Baltimore Longitudinal Study of Aging (BLSA); Alzheimer’s Disease Neuroimaging Initiative (ADNI). Yang Z, et al. Nat Commun. 2021 Dec 3;12(1):7065. doi: 10.1038/s41467-021-26703-z. Nat Commun. 2021. PMID: 34862382 Free PMC article.
Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. Among authors: cui y. ArXiv [Preprint]. 2023 Jan 25:arXiv:2301.10772v1. ArXiv. 2023. Update in: Nat Commun. 2024 Jan 8;15(1):354. doi: 10.1038/s41467-023-44271-2 PMID: 36748000 Free PMC article. Updated. Preprint.
Preference Matrix Guided Sparse Canonical Correlation Analysis for Genetic Study of Quantitative Traits in Alzheimer's Disease.
Sha J, Bao J, Liu K, Yang S, Wen Z, Cui Y, Wen J, Davatzikos C, Moore JH, Saykin AJ, Long Q, Shen L; ADNI. Sha J, et al. Among authors: cui y. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2022 Dec;2022:541-548. doi: 10.1109/bibm55620.2022.9995342. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2022. PMID: 36845995 Free PMC article.
Patterns of Regional Brain Atrophy and Brain Aging in Middle- and Older-Aged Adults With Type 1 Diabetes.
Habes M, Jacobson AM, Braffett BH, Rashid T, Ryan CM, Shou H, Cui Y, Davatzikos C, Luchsinger JA, Biessels GJ, Bebu I, Gubitosi-Klug RA, Bryan RN, Nasrallah IM; DCCT/EDIC Research Group. Habes M, et al. Among authors: cui y. JAMA Netw Open. 2023 Jun 1;6(6):e2316182. doi: 10.1001/jamanetworkopen.2023.16182. JAMA Netw Open. 2023. PMID: 37261829 Free PMC article. Clinical Trial.
Association of brain microbleeds with risk factors, cognition, and MRI markers in MESA.
Jensen PN, Rashid T, Ware JB, Cui Y, Sitlani CM, Austin TR, Longstreth WT Jr, Bertoni AG, Mamourian E, Bryan RN, Nasrallah IM, Habes M, Heckbert SR. Jensen PN, et al. Among authors: cui y. Alzheimers Dement. 2023 Sep;19(9):4139-4149. doi: 10.1002/alz.13346. Epub 2023 Jun 8. Alzheimers Dement. 2023. PMID: 37289978 Free PMC article.
The Genetic Architecture of Multimodal Human Brain Age.
Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C. Wen J, et al. Among authors: cui y. bioRxiv [Preprint]. 2023 Sep 30:2023.04.13.536818. doi: 10.1101/2023.04.13.536818. bioRxiv. 2023. Update in: Nat Commun. 2024 Mar 23;15(1):2604. doi: 10.1038/s41467-024-46796-6 PMID: 37333190 Free PMC article. Updated. Preprint.
The Genetic Architecture of Biological Age in Nine Human Organ Systems.
Wen J, Tian YE, Skampardoni I, Yang Z, Cui Y, Anagnostakis F, Mamourian E, Zhao B, Toga AW, Zaleskey A, Davatzikos C. Wen J, et al. Among authors: cui y. medRxiv [Preprint]. 2024 Jun 11:2023.06.08.23291168. doi: 10.1101/2023.06.08.23291168. medRxiv. 2024. Update in: Nat Aging. 2024 Sep;4(9):1290-1307. doi: 10.1038/s43587-024-00662-8 PMID: 37398441 Free PMC article. Updated. Preprint.
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