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Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer's disease continuum.
Wen J, Yang Z, Nasrallah IM, Cui Y, Erus G, Srinivasan D, Abdulkadir A, Mamourian E, Hwang G, Singh A, Bergman M, Bao J, Varol E, Zhou Z, Boquet-Pujadas A, Chen J, Toga AW, Saykin AJ, Hohman TJ, Thompson PM, Villeneuve S, Gollub R, Sotiras A, Wittfeld K, Grabe HJ, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Benzinger TL, Heckbert SR, Austin TR, Launer LJ, Espeland M, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Resnick SM, Ferrucci L, Fan Y, Habes M, Wolk D, Shen L, Shou H, Davatzikos C. Wen J, et al. Among authors: yang z. Transl Psychiatry. 2024 Oct 5;14(1):420. doi: 10.1038/s41398-024-03121-5. Transl Psychiatry. 2024. PMID: 39368996 Free PMC article.
Multi-scale semi-supervised clustering of brain images: Deriving disease subtypes.
Wen J, Varol E, Sotiras A, Yang Z, Chand GB, Erus G, Shou H, Abdulkadir A, Hwang G, Dwyer DB, Pigoni A, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Rafael RG, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Fan Y, Gur RC, Gur RE, Satterthwaite TD, Koutsouleris N, Wolf DH, Davatzikos C; Alzheimer's Disease Neuroimaging Initiative. Wen J, et al. Among authors: yang z. Med Image Anal. 2022 Jan;75:102304. doi: 10.1016/j.media.2021.102304. Epub 2021 Nov 11. Med Image Anal. 2022. PMID: 34818611 Free PMC article.
A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure.
Yang Z, Nasrallah IM, Shou H, Wen J, Doshi J, Habes M, Erus G, Abdulkadir A, Resnick SM, Albert MS, Maruff P, Fripp J, Morris JC, Wolk DA, Davatzikos C; iSTAGING Consortium; Baltimore Longitudinal Study of Aging (BLSA); Alzheimer’s Disease Neuroimaging Initiative (ADNI). Yang Z, et al. Nat Commun. 2021 Dec 3;12(1):7065. doi: 10.1038/s41467-021-26703-z. Nat Commun. 2021. PMID: 34862382 Free PMC article.
Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.
Wen J, Fu CHY, Tosun D, Veturi Y, Yang Z, Abdulkadir A, Mamourian E, Srinivasan D, Skampardoni I, Singh A, Nawani H, Bao J, Erus G, Shou H, Habes M, Doshi J, Varol E, Mackin RS, Sotiras A, Fan Y, Saykin AJ, Sheline YI, Shen L, Ritchie MD, Wolk DA, Albert M, Resnick SM, Davatzikos C; iSTAGING consortium, ADNI, BIOCARD, and BLSA. Wen J, et al. Among authors: yang z. JAMA Psychiatry. 2022 May 1;79(5):464-474. doi: 10.1001/jamapsychiatry.2022.0020. JAMA Psychiatry. 2022. PMID: 35262657 Free PMC article.
Applications of generative adversarial networks in neuroimaging and clinical neuroscience.
Wang R, Bashyam V, Yang Z, Yu F, Tassopoulou V, Chintapalli SS, Skampardoni I, Sreepada LP, Sahoo D, Nikita K, Abdulkadir A, Wen J, Davatzikos C. Wang R, et al. Among authors: yang z. Neuroimage. 2023 Apr 1;269:119898. doi: 10.1016/j.neuroimage.2023.119898. Epub 2023 Jan 24. Neuroimage. 2023. PMID: 36702211 Free PMC article. Review.
Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering.
Yang Z, Wen J, Abdulkadir A, Cui Y, Erus G, Mamourian E, Melhem R, Srinivasan D, Govindarajan ST, Chen J, Habes M, Masters CL, Maruff P, Fripp J, Ferrucci L, Albert MS, Johnson SC, Morris JC, LaMontagne P, Marcus DS, Benzinger TLS, Wolk DA, Shen L, Bao J, Resnick SM, Shou H, Nasrallah IM, Davatzikos C. Yang Z, et al. ArXiv [Preprint]. 2023 Jan 25:arXiv:2301.10772v1. ArXiv. 2023. Update in: Nat Commun. 2024 Jan 8;15(1):354. doi: 10.1038/s41467-023-44271-2 PMID: 36748000 Free PMC article. Updated. Preprint.
The Genetic Architecture of Multimodal Human Brain Age.
Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C. Wen J, et al. Among authors: yang z. bioRxiv [Preprint]. 2023 Sep 30:2023.04.13.536818. doi: 10.1101/2023.04.13.536818. bioRxiv. 2023. Update in: Nat Commun. 2024 Mar 23;15(1):2604. doi: 10.1038/s41467-024-46796-6 PMID: 37333190 Free PMC article. Updated. Preprint.
The Genetic Architecture of Biological Age in Nine Human Organ Systems.
Wen J, Tian YE, Skampardoni I, Yang Z, Cui Y, Anagnostakis F, Mamourian E, Zhao B, Toga AW, Zaleskey A, Davatzikos C. Wen J, et al. Among authors: yang z. medRxiv [Preprint]. 2024 Jun 11:2023.06.08.23291168. doi: 10.1101/2023.06.08.23291168. medRxiv. 2024. Update in: Nat Aging. 2024 Sep;4(9):1290-1307. doi: 10.1038/s43587-024-00662-8 PMID: 37398441 Free PMC article. Updated. Preprint.
Nine Neuroimaging-AI Endophenotypes Unravel Disease Heterogeneity and Partial Overlap across Four Brain Disorders: A Dimensional Neuroanatomical Representation.
Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah I, Satterthwaite T, Shou H, Shen L, Toga AW, Zalesky A, Davatzikos C. Wen J, et al. Among authors: yang z. medRxiv [Preprint]. 2024 Sep 25:2023.08.16.23294179. doi: 10.1101/2023.08.16.23294179. medRxiv. 2024. PMID: 37662256 Free PMC article. Preprint.
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