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Page 1
Prodrug nanotherapy demonstrates in vivo anticryptosporidial efficacy in a mouse model of chronic Cryptosporidium infection.
Ranjan AP, Czyzyk DJ, Martinez-Traverso G, Sadiqova A, Valhondo M, Schaefer DA, Spasov KA, Jorgensen WL, Vishwanatha JK, Riggs MW, Castellanos-Gonzalez A, Anderson KS. Ranjan AP, et al. Among authors: castellanos gonzalez a. RSC Pharm. 2024 Sep 19;1(5):963-975. doi: 10.1039/d4pm00093e. eCollection 2024 Dec 10. RSC Pharm. 2024. PMID: 39372445 Free PMC article.
Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1.
Zhang Z, Ojo KK, Johnson SM, Larson ET, He P, Geiger JA, Castellanos-Gonzalez A, White AC Jr, Parsons M, Merritt EA, Maly DJ, Verlinde CL, Van Voorhis WC, Fan E. Zhang Z, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5264-7. doi: 10.1016/j.bmcl.2012.06.050. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22795629 Free PMC article.
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium.
Mukerjee A, Iyidogan P, Castellanos-Gonzalez A, Cisneros JA, Czyzyk D, Ranjan AP, Jorgensen WL, White AC Jr, Vishwanatha JK, Anderson KS. Mukerjee A, et al. Bioorg Med Chem Lett. 2015;25(10):2065-7. doi: 10.1016/j.bmcl.2015.03.091. Epub 2015 Apr 4. Bioorg Med Chem Lett. 2015. PMID: 25900220 Free PMC article.
Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
Hulverson MA, Vinayak S, Choi R, Schaefer DA, Castellanos-Gonzalez A, Vidadala RSR, Brooks CF, Herbert GT, Betzer DP, Whitman GR, Sparks HN, Arnold SLM, Rivas KL, Barrett LK, White AC Jr, Maly DJ, Riggs MW, Striepen B, Van Voorhis WC, Ojo KK. Hulverson MA, et al. J Infect Dis. 2017 Apr 15;215(8):1275-1284. doi: 10.1093/infdis/jix120. J Infect Dis. 2017. PMID: 28329187 Free PMC article.
Killing of Cryptosporidium sporozoites by Lactoferrin.
Paredes JL, Sparks H, White AC Jr, Martinez-Traverso G, Ochoa T, Castellanos-González A. Paredes JL, et al. Am J Trop Med Hyg. 2017 Sep;97(3):774-776. doi: 10.4269/ajtmh.16-0804. Epub 2017 Jul 19. Am J Trop Med Hyg. 2017. PMID: 28722573 Free PMC article.
53 results