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19 results

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Page 1
Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein.
Dacon C, Moskovitz R, Swearingen K, Da Silva Pereira L, Flores-Garcia Y, Aleshnick M, Kanatani S, Flynn B, Molina-Cruz A, Wollenberg K, Traver M, Kirtley P, Purser L, Dillon M, Bonilla B, Franco A, Petros S, Kritzberg J, Tucker C, Paez GG, Gupta P, Shears MJ, Pazzi J, Edgar JM, Teng AA, Belmonte A, Oda K, Doumbo S, Krymskaya L, Skinner J, Li S, Ghosal S, Kayentao K, Ongoiba A, Vaughan A, Campo JJ, Traore B, Barillas-Mury C, Wijayalath W, Idris A, Crompton PD, Sinnis P, Wilder BK, Zavala F, Seder RA, Wilson IA, Tan J. Dacon C, et al. Among authors: aleshnick m. Science. 2025 Jan 3;387(6729):eadr0510. doi: 10.1126/science.adr0510. Epub 2025 Jan 3. Science. 2025. PMID: 39745947
Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages.
Winnicki AC, Dietrich MH, Yeoh LM, Carias LL, Roobsoong W, Drago CL, Malachin AN, Redinger KR, Feufack-Donfack LB, Baldor L, Jung NC, McLaine OS, Skomorovska-Prokvolit Y, Orban A, Opi DH, Kirtley P, Nielson K, Aleshnick M, Zanghi G, Rezakhani N, Vaughan AM, Wilder BK, Sattabongkot J, Tham WH, Popovici J, Beeson JG, Bosch J, King CL. Winnicki AC, et al. Among authors: aleshnick m. Nat Commun. 2024 Dec 4;15(1):10556. doi: 10.1038/s41467-024-53848-4. Nat Commun. 2024. PMID: 39632799 Free PMC article.
pr-independent biogenesis of infectious mature Zika virus particles.
Dowd KA, Schroeder M, Sanchez E, Brumbaugh B, Foreman BM, Burgomaster KE, Shi W, Wang L, Caputo N, Gordon DN, Schwartz CL, Hansen BT, Aleshnick M, Kong WP, Morabito KM, Hickman HD, Graham BS, Fischer ER, Pierson TC. Dowd KA, et al. Among authors: aleshnick m. bioRxiv [Preprint]. 2024 Sep 12:2024.09.12.612520. doi: 10.1101/2024.09.12.612520. bioRxiv. 2024. PMID: 39372759 Free PMC article. Preprint.
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Barrett JR, Pipini D, Wright ND, Cooper AJR, Gorini G, Quinkert D, Lias AM, Davies H, Rigby CA, Aleshnick M, Williams BG, Bradshaw WJ, Paterson NG, Martinson T, Kirtley P, Picard L, Wiggins CD, Donnellan FR, King LDW, Wang LT, Popplewell JF, Silk SE, de Ruiter Swain J, Skinner K, Kotraiah V, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Minassian AM, Lauffenburger DA, Miura K, Long CA, Wilder BK, Koekemoer L, Tan J, Nielsen CM, McHugh K, Draper SJ. Barrett JR, et al. Among authors: aleshnick m. Cell. 2024 Sep 5;187(18):4964-4980.e21. doi: 10.1016/j.cell.2024.06.015. Epub 2024 Jul 25. Cell. 2024. PMID: 39059380 Free article.
3-Position Biaryl Endochin-like Quinolones with Enhanced Antimalarial Performance.
Pou S, Winter RW, Dodean RA, Liebman K, Li Y, Mather MW, Nepal B, Nilsen A, Handford MJ, Riscoe TM, Laxson S, Kirtley PJ, Aleshnick M, Zakharov LN, Kelly JX, Smilkstein MJ, Wilder BK, Kortagere S, Vaidya AB, Alday PH, Doggett JS, Riscoe MK. Pou S, et al. Among authors: aleshnick m. ACS Infect Dis. 2024 Jul 12;10(7):2419-2442. doi: 10.1021/acsinfecdis.4c00140. Epub 2024 Jun 11. ACS Infect Dis. 2024. PMID: 38862127
Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages.
Winnicki AC, King CL, Bosch J, Malachin AN, Carias LL, Skomorovska-Prokvolit Y, Tham WH, Dietrich MH, Popovici J, Roobsoong W, Beeson JG, Sattabongkot J, Yeoh LM, Opi DH, Feufack-Donfack LB, Orban A, Drago CL, McLaine OS, Redinger KR, Jung NC, Baldor L, Kirtley P, Neilsen K, Aleshnick M, Zanghi G, Rezakhani N, Vaughan AM, Wilder BK. Winnicki AC, et al. Among authors: aleshnick m. bioRxiv [Preprint]. 2024 Aug 17:2024.02.07.579302. doi: 10.1101/2024.02.07.579302. bioRxiv. 2024. Update in: Nat Commun. 2024 Dec 4;15(1):10556. doi: 10.1038/s41467-024-53848-4 PMID: 38370683 Free PMC article. Updated. Preprint.
Zika virus spreads through infection of lymph node-resident macrophages.
Reynoso GV, Gordon DN, Kalia A, Aguilar CC, Malo CS, Aleshnick M, Dowd KA, Cherry CR, Shannon JP, Vrba SM, Holmes AC, Alippe Y, Maciejewski S, Asano K, Diamond MS, Pierson TC, Hickman HD. Reynoso GV, et al. Among authors: aleshnick m. Cell Rep. 2023 Feb 28;42(2):112126. doi: 10.1016/j.celrep.2023.112126. Epub 2023 Feb 15. Cell Rep. 2023. PMID: 36795561 Free PMC article.
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Dowd KA, Sirohi D, Speer SD, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC. Dowd KA, et al. Among authors: aleshnick m. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218899120. doi: 10.1073/pnas.2218899120. Epub 2023 Jan 13. Proc Natl Acad Sci U S A. 2023. PMID: 36638211 Free PMC article.
Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver.
Franke-Fayard B, Marin-Mogollon C, Geurten FJA, Chevalley-Maurel S, Ramesar J, Kroeze H, Baalbergen E, Wessels E, Baron L, Soulard V, Martinson T, Aleshnick M, Huijs ATG, Subudhi AK, Miyazaki Y, Othman AS, Kolli SK, Lamers OAC, Roques M, Stanway RR, Murphy SC, Foquet L, Moita D, Mendes AM, Prudêncio M, Dechering KJ, Heussler VT, Pain A, Wilder BK, Roestenberg M, Janse CJ. Franke-Fayard B, et al. Among authors: aleshnick m. NPJ Vaccines. 2022 Nov 4;7(1):139. doi: 10.1038/s41541-022-00558-x. NPJ Vaccines. 2022. PMID: 36333336 Free PMC article.
19 results