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Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells.
McCreery KP, Stubb A, Stephens R, Fursova NA, Cook A, Kruse K, Michelbach A, Biggs LC, Keikhosravi A, Nykänen S, Hydén-Granskog C, Zou J, Lackmann JW, Niessen CM, Vuoristo S, Miroshnikova YA, Wickström SA. McCreery KP, et al. Among authors: nykanen s. bioRxiv [Preprint]. 2024 Sep 7:2024.09.07.611779. doi: 10.1101/2024.09.07.611779. bioRxiv. 2024. PMID: 39372762 Free PMC article. Preprint.
DUX4, the rockstar of embryonic genome activation?
Nykänen S, Vuoristo S. Nykänen S, et al. Int J Dev Biol. 2024 May 13. doi: 10.1387/ijdb.230247sn. Online ahead of print. Int J Dev Biol. 2024. PMID: 38770833 Free article.
Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis.
Pussila M, Laiho A, Törönen P, Björkbacka P, Nykänen S, Pylvänäinen K, Holm L, Mecklin JP, Renkonen-Sinisalo L, Lehtonen T, Lepistö A, Linden J, Mäki-Nevala S, Peltomäki P, Nyström M. Pussila M, et al. Among authors: nykanen s. EBioMedicine. 2024 May;103:105111. doi: 10.1016/j.ebiom.2024.105111. Epub 2024 Apr 6. EBioMedicine. 2024. PMID: 38583260 Free PMC article.
Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2.
Yoshihara M, Kirjanov I, Nykänen S, Sokka J, Weltner J, Lundin K, Gawriyski L, Jouhilahti EM, Varjosalo M, Tervaniemi MH, Otonkoski T, Trokovic R, Katayama S, Vuoristo S, Kere J. Yoshihara M, et al. Among authors: nykanen s. Stem Cell Reports. 2022 Jul 12;17(7):1743-1756. doi: 10.1016/j.stemcr.2022.06.002. Epub 2022 Jun 30. Stem Cell Reports. 2022. PMID: 35777358 Free PMC article.
DUX4 is a multifunctional factor priming human embryonic genome activation.
Vuoristo S, Bhagat S, Hydén-Granskog C, Yoshihara M, Gawriyski L, Jouhilahti EM, Ranga V, Tamirat M, Huhtala M, Kirjanov I, Nykänen S, Krjutškov K, Damdimopoulos A, Weltner J, Hashimoto K, Recher G, Ezer S, Paluoja P, Paloviita P, Takegami Y, Kanemaru A, Lundin K, Airenne TT, Otonkoski T, Tapanainen JS, Kawaji H, Murakawa Y, Bürglin TR, Varjosalo M, Johnson MS, Tuuri T, Katayama S, Kere J. Vuoristo S, et al. Among authors: nykanen s. iScience. 2022 Mar 22;25(4):104137. doi: 10.1016/j.isci.2022.104137. eCollection 2022 Apr 15. iScience. 2022. PMID: 35402882 Free PMC article.
SuPAR and PAI-1 in critically ill, mechanically ventilated patients.
Jalkanen V, Yang R, Linko R, Huhtala H, Okkonen M, Varpula T, Pettilä V, Tenhunen J; FINNALI Study Group. Jalkanen V, et al. Intensive Care Med. 2013 Mar;39(3):489-96. doi: 10.1007/s00134-012-2730-x. Epub 2012 Oct 26. Intensive Care Med. 2013. PMID: 23100007
Plasma cell-free DNA in patients needing mechanical ventilation.
Okkonen M, Lakkisto P, Korhonen AM, Parviai-nen I, Reinikainen M, Varpula T, Pettilä V; FINNALI Study Group. Okkonen M, et al. Crit Care. 2011 Aug 12;15(4):R196. doi: 10.1186/cc10357. Crit Care. 2011. PMID: 21838858 Free PMC article.
41 results