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Glia-enriched stem-cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis.
Fagiani F, Pedrini E, Taverna S, Brambilla E, Murtaj V, Podini P, Ruffini F, Butti E, Braccia C, Andolfo A, Magliozzi R, Smirnova L, Kuhlmann T, Quattrini A, Calabresi PA, Reich DS, Martino G, Panina-Bordignon P, Absinta M. Fagiani F, et al. Among authors: ruffini f. bioRxiv [Preprint]. 2024 Jun 24:2024.06.20.597748. doi: 10.1101/2024.06.20.597748. bioRxiv. 2024. Update in: Cell Rep Med. 2024 Aug 20;5(8):101680. doi: 10.1016/j.xcrm.2024.101680 PMID: 39372788 Free PMC article. Updated. Preprint.
Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study.
Genchi A, Brambilla E, Sangalli F, Radaelli M, Bacigaluppi M, Furlan R, Andolfo A, Drago D, Magagnotti C, Scotti GM, Greco R, Vezzulli P, Ottoboni L, Bonopane M, Capilupo D, Ruffini F, Belotti D, Cabiati B, Cesana S, Matera G, Leocani L, Martinelli V, Moiola L, Vago L, Panina-Bordignon P, Falini A, Ciceri F, Uglietti A, Sormani MP, Comi G, Battaglia MA, Rocca MA, Storelli L, Pagani E, Gaipa G, Martino G. Genchi A, et al. Among authors: ruffini f. Nat Med. 2023 Jan;29(1):75-85. doi: 10.1038/s41591-022-02097-3. Epub 2023 Jan 9. Nat Med. 2023. PMID: 36624312 Free PMC article. Clinical Trial.
Neural precursor cells tune striatal connectivity through the release of IGFBPL1.
Butti E, Cattaneo S, Bacigaluppi M, Cambiaghi M, Scotti GM, Brambilla E, Ruffini F, Sferruzza G, Ripamonti M, Simeoni F, Cacciaguerra L, Zanghì A, Quattrini A, Fesce R, Panina-Bordignon P, Giannese F, Cittaro D, Kuhlmann T, D'Adamo P, Rocca MA, Taverna S, Martino G. Butti E, et al. Among authors: ruffini f. Nat Commun. 2022 Dec 8;13(1):7579. doi: 10.1038/s41467-022-35341-y. Nat Commun. 2022. PMID: 36482070 Free PMC article.
Immunological markers in multiple sclerosis.
Gironi M, Bergami A, Brambilla E, Ruffini F, Furlan R, Comi G, Martino G. Gironi M, et al. Among authors: ruffini f. Neurol Sci. 2000;21(4 Suppl 2):S871-5. doi: 10.1007/s100720070029. Neurol Sci. 2000. PMID: 11205366 Review.
Cytokines and immunity in multiple sclerosis: the dual signal hypothesis.
Martino G, Furlan R, Brambilla E, Bergami A, Ruffini F, Gironi M, Poliani PL, Grimaldi LM, Comi G. Martino G, et al. Among authors: ruffini f. J Neuroimmunol. 2000 Sep 1;109(1):3-9. doi: 10.1016/s0165-5728(00)00295-2. J Neuroimmunol. 2000. PMID: 10969174 Review.
Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis.
Starost L, Lindner M, Herold M, Xu YKT, Drexler HCA, Heß K, Ehrlich M, Ottoboni L, Ruffini F, Stehling M, Röpke A, Thomas C, Schöler HR, Antel J, Winkler J, Martino G, Klotz L, Kuhlmann T. Starost L, et al. Among authors: ruffini f. Acta Neuropathol. 2020 Nov;140(5):715-736. doi: 10.1007/s00401-020-02217-8. Epub 2020 Sep 7. Acta Neuropathol. 2020. PMID: 32894330 Free PMC article.
176 results