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Page 1
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing.
Qu Q, Chen Y, Wang Y, Wang W, Long S, Yang HY, Wu J, Li M, Tian X, Wei X, Liu YH, Xu S, Xiong J, Yang C, Wu Z, Huang X, Xie C, Wu Y, Xu Z, Zhang C, Zhang B, Feng JW, Chen J, Feng Y, Fang H, Lin L, Xie ZK, Sun B, Tian H, Yu Y, Piao HL, Xie XS, Deng X, Zhang CS, Lin SC. Qu Q, et al. Among authors: zhang cs. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-08348-2. Online ahead of print. Nature. 2024. PMID: 39695235
Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Qu Q, Chen Y, Wang Y, Long S, Wang W, Yang HY, Li M, Tian X, Wei X, Liu YH, Xu S, Zhang C, Zhu M, Lam SM, Wu J, Yun C, Chen J, Xue S, Zhang B, Zheng ZZ, Piao HL, Jiang C, Guo H, Shui G, Deng X, Zhang CS, Lin SC. Qu Q, et al. Among authors: zhang cs. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-08329-5. Online ahead of print. Nature. 2024. PMID: 39695227
AXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation.
Dai DL, Xie C, Zhong LY, Liu SX, Zhang LL, Zhang H, Wu XP, Wu ZM, Kang K, Li Y, Sun YM, Xia TL, Zhang CS, Zhang A, Shi M, Sun C, Chen ML, Zhao GX, Bu GL, Liu YT, Huang KY, Zhao Z, Li SX, Zhang XY, Yuan YF, Wen SJ, Zhang L, Li BK, Zhong Q, Zeng MS. Dai DL, et al. Among authors: zhang cs. Signal Transduct Target Ther. 2024 Oct 9;9(1):281. doi: 10.1038/s41392-024-01978-y. Signal Transduct Target Ther. 2024. PMID: 39384753 Free PMC article.
AMPK-PDZD8-GLS1 axis mediates calorie restriction-induced lifespan extension.
Li M, Wang Y, Wei X, Cai WF, Liu YH, Wu J, Chen Y, Xiong J, Cui LF, Zhu M, Zhang C, Lin L, Yu Y, Piao HL, Lin SC, Zhang CS. Li M, et al. Among authors: zhang cs. Cell Res. 2024 Nov;34(11):806-809. doi: 10.1038/s41422-024-01021-3. Epub 2024 Sep 19. Cell Res. 2024. PMID: 39300254 Free PMC article. No abstract available.
Lanthanum chloride exerts therapeutic potential for chronic kidney disease by suppressing nanohydroxyapatite-induced mitophagy and mitochondria-mediated apoptosis.
Zhu L, Wang LY, Zhang T, Wang QW, Zhang CS, Zhou ZH, Qian JL, Liang Y, Zhou C, Bu R, Su CH, Dong LS, Wang Y, Du XL, Cao XD, Gao J, Liu Y, Li B, Li G. Zhu L, et al. Among authors: zhang cs. Free Radic Biol Med. 2024 Nov 1;224:554-563. doi: 10.1016/j.freeradbiomed.2024.09.007. Epub 2024 Sep 16. Free Radic Biol Med. 2024. PMID: 39293609
365 results