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Page 1
Type I IFN drives unconventional IL-1β secretion in lupus monocytes.
Caielli S, Balasubramanian P, Rodriguez-Alcazar J, Balaji U, Robinson L, Wan Z, Baisch J, Smitherman C, Walters L, Sparagana P, Nehar-Belaid D, Marches R, Nassi L, Stewart K, Fuller J, Banchereau JF, Gu J, Wright T, Pascual V. Caielli S, et al. Among authors: rodriguez alcazar j. Immunity. 2024 Nov 12;57(11):2497-2513.e12. doi: 10.1016/j.immuni.2024.09.004. Epub 2024 Oct 7. Immunity. 2024. PMID: 39378884
Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model.
Parsons BD, Medina-Luna D, Scur M, Pinelli M, Gamage GS, Chilvers RA, Hamon Y, Ahmed IHI, Savary S, Makrigiannis AP, Braverman NE, Rodriguez-Alcazar JF, Latz E, Karakach TK, Di Cara F. Parsons BD, et al. Among authors: rodriguez alcazar jf. Cell Rep. 2024 Feb 27;43(2):113744. doi: 10.1016/j.celrep.2024.113744. Epub 2024 Feb 6. Cell Rep. 2024. PMID: 38329874 Free article.
An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes.
Caielli S, Balasubramanian P, Rodriguez-Alcazar J, Balaji U, Wan Z, Baisch J, Smitherman C, Walters L, Sparagana P, Nehar-Belaid D, Marches R, Nassi L, Stewart K, Fuller J, Banchereau JF, Gu J, Wright T, Pascual V. Caielli S, et al. Among authors: rodriguez alcazar j. bioRxiv [Preprint]. 2023 Aug 3:2023.08.03.551696. doi: 10.1101/2023.08.03.551696. bioRxiv. 2023. PMID: 37577613 Free PMC article. Preprint.
ATP-binding and hydrolysis of human NLRP3.
Brinkschulte R, Fußhöller DM, Hoss F, Rodríguez-Alcázar JF, Lauterbach MA, Kolbe CC, Rauen M, Ince S, Herrmann C, Latz E, Geyer M. Brinkschulte R, et al. Among authors: rodriguez alcazar jf. Commun Biol. 2022 Nov 3;5(1):1176. doi: 10.1038/s42003-022-04120-2. Commun Biol. 2022. PMID: 36329210 Free PMC article.
Alternative splicing regulates stochastic NLRP3 activity.
Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Hoss F, et al. Among authors: rodriguez alcazar jf. Nat Commun. 2019 Jul 19;10(1):3238. doi: 10.1038/s41467-019-11076-1. Nat Commun. 2019. PMID: 31324763 Free PMC article.
Assembly and regulation of ASC specks.
Hoss F, Rodriguez-Alcazar JF, Latz E. Hoss F, et al. Among authors: rodriguez alcazar jf. Cell Mol Life Sci. 2017 Apr;74(7):1211-1229. doi: 10.1007/s00018-016-2396-6. Epub 2016 Oct 19. Cell Mol Life Sci. 2017. PMID: 27761594 Free PMC article. Review.
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