Gogliotti RG - Search Results

1

Site-blocking antisense oligonucleotides as a mechanism to fine-tune MeCP2 expression.

Vanderplow AM, Dodis GE, Rhee Y, Cikowski JJ, Gonzalez S, Smith ML, Gogliotti RG. Vanderplow AM, et al. Among authors: gogliotti rg. RNA. 2024 Nov 18;30(12):1554-1571. doi: 10.1261/rna.080220.124. RNA. 2024. PMID: 39379106 Free PMC article.

2

Potentiation of the M ₁ muscarinic acetylcholine receptor normalizes neuronal activation patterns and improves apnea severity in Mecp2^+/- mice.

Smith M, Dodis GE, Vanderplow AM, Gonzalez S, Rhee Y, Gogliotti RG. Smith M, et al. Among authors: gogliotti rg. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.586099. doi: 10.1101/2024.04.15.586099. bioRxiv. 2024. PMID: 38659804 Free PMC article. Preprint.

3

MeCP2 gene therapy ameliorates disease phenotype in mouse model for Pitt Hopkins syndrome.

Dennys CN, Vermudez SAD, Deacon RJM, Sierra-Delgado JA, Rich K, Zhang X, Buch A, Weiss K, Moxley Y, Rajpal H, Espinoza FD, Powers S, Ávila AS, Gogliotti RG, Cogram P, Niswender CM, Meyer KC. Dennys CN, et al. Among authors: gogliotti rg. Neurotherapeutics. 2024 Sep;21(5):e00376. doi: 10.1016/j.neurot.2024.e00376. Epub 2024 Jun 14. Neurotherapeutics. 2024. PMID: 38876822 Free PMC article.

4

Optimized Administration of the M₄ PAM VU0467154 Demonstrates Broad Efficacy, but Limited Effective Concentrations in Mecp2^+/- Mice.

Cikowski J, Holt C, Arthur B, Smith M, Gonzalez S, Lindsley CW, Niswender CM, Gogliotti RG. Cikowski J, et al. Among authors: gogliotti rg. ACS Chem Neurosci. 2022 Jul 6;13(13):1891-1901. doi: 10.1021/acschemneuro.2c00113. Epub 2022 Jun 7. ACS Chem Neurosci. 2022. PMID: 35671352 Free PMC article.

5

Clinical and Preclinical Evidence for M₁ Muscarinic Acetylcholine Receptor Potentiation as a Therapeutic Approach for Rett Syndrome.

Smith M, Arthur B, Cikowski J, Holt C, Gonzalez S, Fisher NM, Vermudez SAD, Lindsley CW, Niswender CM, Gogliotti RG. Smith M, et al. Among authors: gogliotti rg. Neurotherapeutics. 2022 Jul;19(4):1340-1352. doi: 10.1007/s13311-022-01254-3. Epub 2022 Jun 7. Neurotherapeutics. 2022. PMID: 35670902 Free PMC article.

6

Exploration of group II metabotropic glutamate receptor modulation in mouse models of Rett syndrome and MECP2 Duplication syndrome.

Vermudez SAD, Buch A, Weiss K, Gogliotti RG, Niswender CM. Vermudez SAD, et al. Among authors: gogliotti rg. Neuropharmacology. 2022 May 15;209:109022. doi: 10.1016/j.neuropharm.2022.109022. Epub 2022 Mar 3. Neuropharmacology. 2022. PMID: 35248529 Free PMC article.

7

Profiling beneficial and potential adverse effects of MeCP2 overexpression in a hypomorphic Rett syndrome mouse model.

Vermudez SAD, Gogliotti RG, Arthur B, Buch A, Morales C, Moxley Y, Rajpal H, Conn PJ, Niswender CM. Vermudez SAD, et al. Among authors: gogliotti rg. Genes Brain Behav. 2022 Jan;21(1):e12752. doi: 10.1111/gbb.12752. Epub 2021 May 28. Genes Brain Behav. 2022. PMID: 34002468 Free PMC article.

8

Activating mGlu₃ Metabotropic Glutamate Receptors Rescues Schizophrenia-like Cognitive Deficits Through Metaplastic Adaptations Within the Hippocampus.

Dogra S, Stansley BJ, Xiang Z, Qian W, Gogliotti RG, Nicoletti F, Lindsley CW, Niswender CM, Joffe ME, Conn PJ. Dogra S, et al. Among authors: gogliotti rg. Biol Psychiatry. 2021 Sep 15;90(6):385-398. doi: 10.1016/j.biopsych.2021.02.970. Epub 2021 Mar 6. Biol Psychiatry. 2021. PMID: 33965197 Free PMC article.

9

A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes.

Fisher NM, AlHashim A, Buch AB, Badivuku H, Samman MM, Weiss KM, Cestero GI, Does MD, Rook JM, Lindsley CW, Conn PJ, Gogliotti RG, Niswender CM. Fisher NM, et al. Among authors: gogliotti rg. JCI Insight. 2021 Feb 22;6(4):e143324. doi: 10.1172/jci.insight.143324. JCI Insight. 2021. PMID: 33476302 Free PMC article.

10

In Vitro to in Vivo Translation of Allosteric Modulator Concentration-Effect Relationships: Implications for Drug Discovery.

Gregory KJ, Bridges TM, Gogliotti RG, Stauffer SR, Noetzel MJ, Jones CK, Lindsley CW, Conn PJ, Niswender CM. Gregory KJ, et al. Among authors: gogliotti rg. ACS Pharmacol Transl Sci. 2019 Nov 15;2(6):442-452. doi: 10.1021/acsptsci.9b00062. eCollection 2019 Dec 13. ACS Pharmacol Transl Sci. 2019. PMID: 32259076 Free PMC article.

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