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Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B.
Meleddu R, Fais A, Era B, Floris S, Distinto S, Lupia A, Cottiglia F, Onali A, Sanna E, Secci D, Atzeni G, Demuru L, Caboni P, Valenti D, Maccioni E. Meleddu R, et al. Among authors: lupia a. ACS Med Chem Lett. 2024 Sep 27;15(10):1685-1691. doi: 10.1021/acsmedchemlett.4c00246. eCollection 2024 Oct 10. ACS Med Chem Lett. 2024. PMID: 39411531
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
Rapacciuolo P, Finamore C, Giorgio CD, Fiorillo B, Massa C, Urbani G, Marchianò S, Bordoni M, Cassiano C, Morretta E, Spinelli L, Lupia A, Moraca F, Biagioli M, Sepe V, Monti MC, Catalanotti B, Fiorucci S, Zampella A. Rapacciuolo P, et al. Among authors: lupia a. J Med Chem. 2024 Oct 24;67(20):18334-18355. doi: 10.1021/acs.jmedchem.4c01651. Epub 2024 Oct 9. J Med Chem. 2024. PMID: 39382988
A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.
Spriano F, Sartori G, Sgrignani J, Barnabei L, Arribas AJ, Guala M, Del Amor AMC, Tomasso MR, Tarantelli C, Cascione L, Golino G, Riveiro ME, Bortolozzi R, Lupia A, Paduano F, Huguet S, Rezai K, Rinaldi A, Margheriti F, Ventura P, Guarda G, Costa G, Rocca R, Furlan A, Verdonk LM, Innocenti P, Martin NI, Viola G, Driessen C, Zucca E, Stathis A, Gahtory D, Van den Nieuwboer M, Bornhauser B, Alcaro S, Trapasso F, Cristobal S, Padrick SB, Pazzi N, Cavalli F, Cavalli A, Gaudio E, Bertoni F. Spriano F, et al. Among authors: lupia a. Haematologica. 2024 Nov 1;109(11):3602-3614. doi: 10.3324/haematol.2022.282672. Haematologica. 2024. PMID: 38899342 Free PMC article.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Di Giorgio C, Morretta E, Lupia A, Bellini R, Massa C, Urbani G, Bordoni M, Marchianò S, Lachi G, Rapacciuolo P, Finamore C, Sepe V, Chiara Monti M, Moraca F, Natalizi N, Graziosi L, Distrutti E, Biagioli M, Catalanotti B, Donini A, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: lupia a. Biochem Pharmacol. 2024 May;223:116134. doi: 10.1016/j.bcp.2024.116134. Epub 2024 Mar 15. Biochem Pharmacol. 2024. PMID: 38494064 Free article.
Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation.
Falanga AP, Lupia A, Tripodi L, Morgillo CM, Moraca F, Roviello GN, Catalanotti B, Amato J, Pastore L, Cerullo V, D'Errico S, Piccialli G, Oliviero G, Borbone N. Falanga AP, et al. Among authors: lupia a. Heliyon. 2024 Jan 22;10(3):e24599. doi: 10.1016/j.heliyon.2024.e24599. eCollection 2024 Feb 15. Heliyon. 2024. PMID: 38317891 Free PMC article.
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Di Giorgio C, Bellini R, Lupia A, Massa C, Urbani G, Bordoni M, Marchianò S, Rosselli R, De Gregorio R, Rapacciuolo P, Sepe V, Morretta E, Monti MC, Moraca F, Cari L, Ullah KRS, Natalizi N, Graziosi L, Distrutti E, Biagioli M, Catalanotti B, Donini A, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: lupia a. Cell Oncol (Dordr). 2024 Apr;47(2):695-710. doi: 10.1007/s13402-023-00893-8. Epub 2023 Nov 9. Cell Oncol (Dordr). 2024. PMID: 37945798 Free PMC article.
50 results