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Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies.
Rubin DT, Allegretti JR, Panés J, Shipitofsky N, Yarandi SS, Huang KG, Germinaro M, Wilson R, Zhang H, Johanns J, Feagan BG, Hisamatsu T, Lichtenstein GR, Bressler B, Peyrin-Biroulet L, Sands BE, Dignass A; QUASAR Study Group. Rubin DT, et al. Lancet. 2025 Jan 4;405(10472):33-49. doi: 10.1016/S0140-6736(24)01927-5. Epub 2024 Dec 17. Lancet. 2025. PMID: 39706209 Clinical Trial.
Preclinical Protein Signatures of Crohn's Disease and Ulcerative Colitis: A Nested Case-Control Study Within Large Population-Based Cohorts.
Grännö O, Bergemalm D, Salomon B, Lindqvist CM, Hedin CRH, Carlson M, Dannenberg K, Andersson E, Keita ÅV, Magnusson MK, Eriksson C, Lanka V; BIOIBD consortium; Magnusson PKE, D'Amato M, Öhman L, Söderholm JD, Hultdin J, Kruse R, Cao Y, Repsilber D, Grip O, Karling P, Halfvarson J. Grännö O, et al. Among authors: hedin crh. Gastroenterology. 2024 Nov 26:S0016-5085(24)05741-X. doi: 10.1053/j.gastro.2024.11.006. Online ahead of print. Gastroenterology. 2024. PMID: 39608683 Free article.
Characterisation of IBD heterogeneity using serum proteomics: A multicentre study.
Salomon B, Sudhakar P, Bergemalm D, Andersson E, Grännö O, Carlson M, Hedin CRH, Söderholm JD, Öhman L; BIO IBD consortium; COLLIBRI consortium; Lindqvist CM, Kruse R, Repsilber D, Verstockt B, Vermeire S, Halfvarson J. Salomon B, et al. Among authors: hedin crh. J Crohns Colitis. 2024 Nov 4:jjae169. doi: 10.1093/ecco-jcc/jjae169. Online ahead of print. J Crohns Colitis. 2024. PMID: 39495605
Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.
Lee SH, Bushra M, Qiu L, Griffiths AM, Turpin W, Croitoru K; Crohn’s and Colitis Canada-Genetic, Environmental, Microbial (CCC-GEM) Project Research Consortium; Lee SH, Bushra M, Qiu L, Shao J, Olivera PA, Leibovitzh H, Xue M, Xu W, Espin-Garcia O, Amuais GL, Huynh HQ, Panaccione R, Steinhart AH, Cino M, Mack D, Marshall J, Ropeleski M, Bitton A, Jacobson K, McGrath J, Yerushalmi B, Abreu MT, Bernstein CN, Radford-Smith G, Lees C, Turner D, Madsen K, Guttman DS, Silverberg M, Griffiths AM, Moayyedi P, Turpin W, Beck P, Dieleman L, Feagan BG, Kaplan G, Krause DO, Seidman E, Snapper S, Stadnyk A, Surette M, Walters T, Vallance B, Critch J, Denson L, Deslandres C, El-Matary W, Herfarth H, Higgins P, Hyams J, Otley A, Hedin C, Hussey S, Keljo D, Kevans D, Murthy S, Parekh N, Plamondon S, Rosh J, Rubin D, Schultz M, Siegel C, Croitoru K. Lee SH, et al. Among authors: hedin c. Gastroenterology. 2024 Oct 9:S0016-5085(24)05539-2. doi: 10.1053/j.gastro.2024.09.033. Online ahead of print. Gastroenterology. 2024. PMID: 39384162 Free article. No abstract available.
Faecal biomarkers for diagnosis and prediction of disease course in treatment-naïve patients with IBD.
Ling Lundström M, Peterson C, Hedin CRH, Bergemalm D, Lampinen M, Magnusson MK, Keita ÅV, Kruse R, Lindqvist CM, Repsilber D, D'Amato M, Hjortswang H, Strid H; BIOIBD Consortium; Söderholm JD, Öhman L, Venge P, Halfvarson J, Carlson M. Ling Lundström M, et al. Among authors: hedin crh. Aliment Pharmacol Ther. 2024 Sep;60(6):765-777. doi: 10.1111/apt.18154. Epub 2024 Jul 12. Aliment Pharmacol Ther. 2024. PMID: 38997818
Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease.
Salihovic S, Nyström N, Mathisen CB, Kruse R, Olbjørn C, Andersen S, Noble AJ, Dorn-Rasmussen M, Bazov I, Perminow G, Opheim R, Detlie TE, Huppertz-Hauss G, Hedin CRH, Carlson M, Öhman L, Magnusson MK, Keita ÅV, Söderholm JD, D'Amato M, Orešič M, Wewer V, Satsangi J, Lindqvist CM, Burisch J, Uhlig HH, Repsilber D, Hyötyläinen T, Høivik ML, Halfvarson J. Salihovic S, et al. Among authors: hedin crh. Nat Commun. 2024 Jun 3;15(1):4567. doi: 10.1038/s41467-024-48763-7. Nat Commun. 2024. PMID: 38830848 Free PMC article.
A Core Outcome Set for Inflammatory Bowel Diseases: Development and Recommendations for Implementation in Clinical Practice Through an International Multi-stakeholder Consensus Process.
Fierens L, Carney N, Novacek G, van der Woude CJ, Siegmund B, Casellas F, Borruel N, Huberts AS, Sonnenberg E, Gerold N, Primas C, Hedin CRH, Stamm T, Julsgaard M, Fiorino G, Radice S, Zini MLL, Gross E, Sander C, Arijs I, Vakouftsi VR, Koltai T, Health Outcomes Observatory H O Patient Advisory Board For Inflammatory Bowel Diseases, Health Outcomes Observatory H O Steering Committee, Charlafti I, Ferrante M. Fierens L, et al. Among authors: hedin crh. J Crohns Colitis. 2024 Oct 15;18(10):1583-1595. doi: 10.1093/ecco-jcc/jjad195. J Crohns Colitis. 2024. PMID: 38019894
87 results