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MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression.
Azambuja JH, Yerneni SS, Maurer LM, Crentsil HE, Debom GN, Klei L, Smyers M, Sneiderman CT, Schwab KE, Acharya R, Wu YL, Ekambaram P, Hu D, Gough PJ, Bertin J, Melnick A, Kohanbash G, Bao R, Lucas PC, McAllister-Lucas LM. Azambuja JH, et al. Among authors: mcallister lucas lm. bioRxiv [Preprint]. 2024 Sep 27:2024.09.26.614808. doi: 10.1101/2024.09.26.614808. bioRxiv. 2024. PMID: 39386586 Free PMC article. Preprint.
Immunocompetent murine model of Ewing sarcoma reveals role for TGFβ inhibition to enhance immune infiltrates in Ewing tumors during radiation.
Daley JD, Mukherjee E, Tufino AC, Bailey N, Bhaskar S, Periyapatna N, MacFawn I, Kunning S, Hinck C, Bruno T, Olson AC, McAllister-Lucas LM, Hinck AP, Cooper K, Bao R, Cillo AR, Bailey KM. Daley JD, et al. Among authors: mcallister lucas lm. bioRxiv [Preprint]. 2024 May 10:2024.05.07.592974. doi: 10.1101/2024.05.07.592974. bioRxiv. 2024. PMID: 38766091 Free PMC article. Preprint.
BRCA1-associated RING domain-1 (BARD1) loss and GBP1 expression enhance sensitivity to DNA damage in Ewing sarcoma.
Maurer LM, Daley JD, Mukherjee E, Venier RE, Julian CM, Bailey NG, Jacobs MF, Kumar-Sinha C, Raphael H, Periyapatna N, Weiss K, Janeway KA, Mody R, Lucas PC, McAllister-Lucas LM, Bailey KM. Maurer LM, et al. Among authors: mcallister lucas lm. Cancer Res Commun. 2022 Apr;2(4):220-232. doi: 10.1158/2767-9764.crc-21-0047. Epub 2022 Apr 20. Cancer Res Commun. 2022. PMID: 36187937 Free PMC article.
MALT1 Is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-Low, Triple-Negative Breast Cancer.
Lee JL, Ekambaram P, Carleton NM, Hu D, Klei LR, Cai Z, Myers MI, Hubel NE, Covic L, Agnihotri S, Krappmann D, Bornancin F, Lee AV, Oesterreich S, McAllister-Lucas LM, Lucas PC. Lee JL, et al. Among authors: mcallister lucas lm. Mol Cancer Res. 2022 Mar 1;20(3):373-386. doi: 10.1158/1541-7786.MCR-21-0208. Mol Cancer Res. 2022. PMID: 34753803 Free PMC article.
Canonical and Non-Canonical Roles of GRK2 in Lymphocytes.
Cheng J, Lucas PC, McAllister-Lucas LM. Cheng J, et al. Among authors: mcallister lucas lm. Cells. 2021 Feb 3;10(2):307. doi: 10.3390/cells10020307. Cells. 2021. PMID: 33546162 Free PMC article. Review.
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein.
Cheng J, Klei LR, Hubel NE, Zhang M, Schairer R, Maurer LM, Klei HB, Kang H, Concel VJ, Delekta PC, Dang EV, Mintz MA, Baens M, Cyster JG, Parameswaran N, Thome M, Lucas PC, McAllister-Lucas LM. Cheng J, et al. Among authors: mcallister lucas lm. J Clin Invest. 2020 Feb 3;130(2):1036-1051. doi: 10.1172/JCI97040. J Clin Invest. 2020. PMID: 31961340 Free PMC article.
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