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SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers.
Hosseinpour M, Xi X, Liu L, Malaver-Ortega L, Perlaza-Jimenez L, Joo JE, York HM, Beesley J, Caldon CE, Dugué PA, Dowty JG, Arumugam S, Southey MC, Rosenbluh J. Hosseinpour M, et al. Among authors: dowty jg. Nat Commun. 2024 Dec 1;15(1):10449. doi: 10.1038/s41467-024-54824-8. Nat Commun. 2024. PMID: 39617792 Free PMC article.
Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma.
Alpen K, Maclnnis RJ, Vajdic CM, Lai J, Dowty JG, Koh ES, Hovey E, Harrup R, Nguyen TL, Li S, Joseph D, Benke G, Dugué PA, Southey MC, Giles GG, Nowak AK, Drummond KJ, Schmidt DF, Hopper JL, Kapuscinski MK, Makalic E. Alpen K, et al. Among authors: dowty jg. Cancer Res Commun. 2024 Nov 1;4(11):2933-2946. doi: 10.1158/2767-9764.CRC-24-0385. Cancer Res Commun. 2024. PMID: 39387520 Free PMC article.
Germline CDH1 Variants and Lifetime Cancer Risk.
Ryan CE, Fasaye GA, Gallanis AF, Gamble LA, McClelland PH, Duemler A, Samaranayake SG, Blakely AM, Drogan CM, Kingham K, Patel D, Rodgers-Fouche L, Siegel A, Kupfer SS, Ford JM, Chung DC, Dowty JG, Sampson J, Davis JL. Ryan CE, et al. Among authors: dowty jg. JAMA. 2024 Sep 3;332(9):722-729. doi: 10.1001/jama.2024.10852. JAMA. 2024. PMID: 38873722 Free PMC article.
Breast and bowel cancers diagnosed in people 'too young to have cancer': A blueprint for research using family and twin studies.
Hopper JL, Li S, MacInnis RJ, Dowty JG, Nguyen TL, Bui M, Dite GS, Esser VFC, Ye Z, Makalic E, Schmidt DF, Goudey B, Alpen K, Kapuscinski M, Win AK, Dugué PA, Milne RL, Jayasekara H, Brooks JD, Malta S, Calais-Ferreira L, Campbell AC, Young JT, Nguyen-Dumont T, Sung J, Giles GG, Buchanan D, Winship I, Terry MB, Southey MC, Jenkins MA. Hopper JL, et al. Among authors: dowty jg. Genet Epidemiol. 2024 Dec;48(8):433-447. doi: 10.1002/gepi.22555. Epub 2024 Mar 19. Genet Epidemiol. 2024. PMID: 38504141 Free PMC article.
Causation and familial confounding as explanations for the associations of polygenic risk scores with breast cancer: Evidence from innovative ICE FALCON and ICE CRISTAL analyses.
Li S, Dite GS, MacInnis RJ, Bui M, Nguyen TL, Esser VFC, Ye Z, Dowty JG, Makalic E, Sung J, Giles GG, Southey MC, Hopper JL. Li S, et al. Among authors: dowty jg. Genet Epidemiol. 2024 Dec;48(8):401-413. doi: 10.1002/gepi.22556. Epub 2024 Mar 12. Genet Epidemiol. 2024. PMID: 38472646 Free PMC article.
Genetic and Environmental Causes of Variation in an Automated Breast Cancer Risk Factor Based on Mammographic Textures.
Ye Z, Dite GS, Nguyen TL, MacInnis RJ, Schmidt DF, Makalic E, Al-Qershi OM, Nguyen-Dumont T, Goudey B, Stone J, Dowty JG, Giles GG, Southey MC, Hopper JL, Li S. Ye Z, et al. Among authors: dowty jg. Cancer Epidemiol Biomarkers Prev. 2024 Feb 6;33(2):306-313. doi: 10.1158/1055-9965.EPI-23-1012. Cancer Epidemiol Biomarkers Prev. 2024. PMID: 38059829
Causal relationships between breast cancer risk factors based on mammographic features.
Ye Z, Nguyen TL, Dite GS, MacInnis RJ, Schmidt DF, Makalic E, Al-Qershi OM, Bui M, Esser VFC, Dowty JG, Trinh HN, Evans CF, Tan M, Sung J, Jenkins MA, Giles GG, Southey MC, Hopper JL, Li S. Ye Z, et al. Among authors: dowty jg. Breast Cancer Res. 2023 Oct 25;25(1):127. doi: 10.1186/s13058-023-01733-1. Breast Cancer Res. 2023. PMID: 37880807 Free PMC article.
Variance of age-specific log incidence decomposition (VALID): a unifying model of measured and unmeasured genetic and non-genetic risks.
Hopper JL, Dowty JG, Nguyen TL, Li S, Dite GS, MacInnis RJ, Makalic E, Schmidt DF, Bui M, Stone J, Sung J, Jenkins MA, Giles GG, Southey MC, Mathews JD. Hopper JL, et al. Among authors: dowty jg. Int J Epidemiol. 2023 Oct 5;52(5):1557-1568. doi: 10.1093/ije/dyad086. Int J Epidemiol. 2023. PMID: 37349888 Free PMC article.
The Colorectal cancer RISk Prediction (CRISP) trial: a randomised controlled trial of a decision support tool for risk-stratified colorectal cancer screening.
Emery JD, Jenkins MA, Saya S, Chondros P, Oberoi J, Milton S, Novy K, Habgood E, Karnchanachari N, Pirotta M, Trevena L, Bickerstaffe A, De Abreu Lourenço R, Crothers A, Ouakrim DA, Flander L, Dowty JG, Walter FM, Clark M, Doncovio S, Etemadmoghadam D, Fishman G, Macrae F, Winship I, McIntosh JG. Emery JD, et al. Among authors: dowty jg. Br J Gen Pract. 2023 Jul 27;73(733):e556-e565. doi: 10.3399/BJGP.2022.0480. Print 2023 Aug. Br J Gen Pract. 2023. PMID: 37012077 Free PMC article. Clinical Trial.
86 results