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High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson's disease.
Williams D, Glasstetter LM, Jong TT, Chen T, Kapoor A, Zhu S, Zhu Y, Calvo R, Gehrlein A, Wong K, Hogan AN, Vocadlo DJ, Jagasia R, Marugan JJ, Sidransky E, Henderson MJ, Chen Y. Williams D, et al. Among authors: kapoor a. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2406009121. doi: 10.1073/pnas.2406009121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388267 Free PMC article.
Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease.
Williams D, Glasstetter LM, Jong TT, Kapoor A, Zhu S, Zhu Y, Gehrlein A, Vocadlo DJ, Jagasia R, Marugan JJ, Sidransky E, Henderson MJ, Chen Y. Williams D, et al. Among authors: kapoor a. bioRxiv [Preprint]. 2024 Mar 27:2024.03.22.586364. doi: 10.1101/2024.03.22.586364. bioRxiv. 2024. PMID: 38712038 Free PMC article. Preprint.
Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis.
Ippolitov D, Lin YH, Spence J, Glogowska A, Thanasupawat T, Beiko J, Del Bigio MR, Xu X, Wang A, Calvo R, Kapoor A, Marugan JJ, Henderson MJ, Klonisch T, Hombach-Klonisch S. Ippolitov D, et al. Among authors: kapoor a. bioRxiv [Preprint]. 2024 Feb 22:2024.02.19.581073. doi: 10.1101/2024.02.19.581073. bioRxiv. 2024. PMID: 38529509 Free PMC article. Preprint.
Phenotype plasticity and altered sensitivity to chemotherapeutic agents in aggressive prostate cancer cells.
Paxson AI, Chang LH, Gard JMC, Harryman WL, Nelson CS, Salmon SB, Marr KD, Wachsmuth LM, Ramanathan A, Ran J, Kapoor A, Marugan JJ, Henderson MJ, Sanchez TW, Cress AE. Paxson AI, et al. Among authors: kapoor a. Front Cell Dev Biol. 2023 Nov 16;11:1285372. doi: 10.3389/fcell.2023.1285372. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38046670 Free PMC article.
Unravelling Eribulin's role in metastatic breast cancer: evaluating benefits for both triple negative and non-triple negative patients in real-world scenarios in resource-constrained settings.
Kapoor A, Gupta A, Sansar B, Gupta P, Mishra BK, Singh A, Upadhyay A, Kumar A, Tripathi M, Chowdhury Z, Patne S, Dhal I, Singh N, Shukla S, Singh SN, Pujari L, Giridhar P, Kapoor AR, Jain Y, Venkatachalam M, Dey S, Vinayak KR. Kapoor A, et al. Among authors: kapoor ar. Ecancermedicalscience. 2024 Nov 28;18:1804. doi: 10.3332/ecancer.2024.1804. eCollection 2024. Ecancermedicalscience. 2024. PMID: 39816379 Free PMC article.
ZFAND6 promotes TRAF2-dependent mitophagy to restrain cGAS-STING signaling.
Shaikh K, Bowman M, McCormick SM, Gao L, Zhang J, White J, Tawil J, Kapoor A, Arav-Boger R, Norbury CC, Harhaj EW. Shaikh K, et al. Among authors: kapoor a. iScience. 2024 Dec 6;28(1):111544. doi: 10.1016/j.isci.2024.111544. eCollection 2025 Jan 17. iScience. 2024. PMID: 39811672 Free PMC article.
2,226 results