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High-throughput screening for small-molecule stabilizers of misfolded glucocerebrosidase in Gaucher disease and Parkinson's disease.
Williams D, Glasstetter LM, Jong TT, Chen T, Kapoor A, Zhu S, Zhu Y, Calvo R, Gehrlein A, Wong K, Hogan AN, Vocadlo DJ, Jagasia R, Marugan JJ, Sidransky E, Henderson MJ, Chen Y. Williams D, et al. Among authors: vocadlo dj. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2406009121. doi: 10.1073/pnas.2406009121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388267 Free PMC article.
The emerging link between O-GlcNAc and Alzheimer disease.
Zhu Y, Shan X, Yuzwa SA, Vocadlo DJ. Zhu Y, et al. Among authors: vocadlo dj. J Biol Chem. 2014 Dec 12;289(50):34472-81. doi: 10.1074/jbc.R114.601351. Epub 2014 Oct 21. J Biol Chem. 2014. PMID: 25336656 Free PMC article. Review.
Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome.
King DT, Serrano-Negrón JE, Zhu Y, Moore CL, Shoulders MD, Foster LJ, Vocadlo DJ. King DT, et al. Among authors: vocadlo dj. J Am Chem Soc. 2022 Mar 9;144(9):3833-3842. doi: 10.1021/jacs.1c10621. Epub 2022 Mar 1. J Am Chem Soc. 2022. PMID: 35230102 Free PMC article.
183 results