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Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations.
Ross JL, Puigdelloses-Vallcorba M, Piñero G, Soni N, Thomason W, DeSisto J, Angione A, Tsankova NM, Castro MG, Schniederjan M, Wadhwani NR, Raju GP, Morgenstern P, Becher OJ, Green AL, Tsankov AM, Hambardzumyan D. Ross JL, et al. Among authors: becher oj. Immunity. 2024 Nov 12;57(11):2669-2687.e6. doi: 10.1016/j.immuni.2024.09.007. Epub 2024 Oct 11. Immunity. 2024. PMID: 39395421
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Ross JL, Chen Z, Herting CJ, Grabovska Y, Szulzewsky F, Puigdelloses M, Monterroza L, Switchenko J, Wadhwani NR, Cimino PJ, Mackay A, Jones C, Read RD, MacDonald TJ, Schniederjan M, Becher OJ, Hambardzumyan D. Ross JL, et al. Among authors: becher oj. Brain. 2021 Feb 12;144(1):53-69. doi: 10.1093/brain/awaa382. Brain. 2021. PMID: 33300045 Free PMC article.
Tumour immune landscape of paediatric high-grade gliomas.
Ross JL, Velazquez Vega J, Plant A, MacDonald TJ, Becher OJ, Hambardzumyan D. Ross JL, et al. Among authors: becher oj. Brain. 2021 Oct 22;144(9):2594-2609. doi: 10.1093/brain/awab155. Brain. 2021. PMID: 33856022 Free PMC article. Review.
A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell-of-origin dependent effects of H3K27M.
Tomita Y, Shimazu Y, Somasundaram A, Tanaka Y, Takata N, Ishi Y, Gadd S, Hashizume R, Angione A, Pinero G, Hambardzumyan D, Brat DJ, Hoeman CM, Becher OJ. Tomita Y, et al. Among authors: becher oj. Glia. 2022 Sep;70(9):1681-1698. doi: 10.1002/glia.24189. Epub 2022 May 7. Glia. 2022. PMID: 35524725 Free PMC article.
Cancer stem cells and survival pathways.
Hambardzumyan D, Becher OJ, Holland EC. Hambardzumyan D, et al. Among authors: becher oj. Cell Cycle. 2008 May 15;7(10):1371-8. doi: 10.4161/cc.7.10.5954. Epub 2008 Mar 19. Cell Cycle. 2008. PMID: 18421251 Review.
A tumor suppressor role for EZH2 in diffuse midline glioma pathogenesis.
Dhar S, Gadd S, Patel P, Vaynshteyn J, Raju GP, Hashizume R, Brat DJ, Becher OJ. Dhar S, et al. Among authors: becher oj. Acta Neuropathol Commun. 2022 Apr 8;10(1):47. doi: 10.1186/s40478-022-01336-5. Acta Neuropathol Commun. 2022. PMID: 35395831 Free PMC article.
Genetic and epigenetic instability as an underlying driver of progression and aggressive behavior in IDH-mutant astrocytoma.
Richardson TE, Walker JM, Hambardzumyan D, Brem S, Hatanpaa KJ, Viapiano MS, Pai B, Umphlett M, Becher OJ, Snuderl M, McBrayer SK, Abdullah KG, Tsankova NM. Richardson TE, et al. Among authors: becher oj. Acta Neuropathol. 2024 Jul 16;148(1):5. doi: 10.1007/s00401-024-02761-7. Acta Neuropathol. 2024. PMID: 39012509 Free PMC article. Review.
Modeling Adult Gliomas Using RCAS/t-va Technology.
Hambardzumyan D, Amankulor NM, Helmy KY, Becher OJ, Holland EC. Hambardzumyan D, et al. Among authors: becher oj. Transl Oncol. 2009 May;2(2):89-95. doi: 10.1593/tlo.09100. Transl Oncol. 2009. PMID: 19412424 Free PMC article.
85 results