Cohen TJ - Search Results

1

Development and characterization of novel anti-acetylated tau monoclonal antibodies to probe pathogenic tau species in Alzheimer's disease.

Bryan Iii MR, Tian X, Tseng JH, Evangelista BA, Ragusa JV, Bryan AF, Trotman W, Irwin D, Cohen TJ. Bryan Iii MR, et al. Among authors: cohen tj. Acta Neuropathol Commun. 2024 Oct 12;12(1):163. doi: 10.1186/s40478-024-01865-1. Acta Neuropathol Commun. 2024. PMID: 39396065 Free PMC article.

2

An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.

Trzeciakiewicz H, Ajit D, Tseng JH, Chen Y, Ajit A, Tabassum Z, Lobrovich R, Peterson C, Riddick NV, Itano MS, Tripathy A, Moy SS, Lee VMY, Trojanowski JQ, Irwin DJ, Cohen TJ. Trzeciakiewicz H, et al. Among authors: cohen tj. Nat Commun. 2020 Nov 2;11(1):5522. doi: 10.1038/s41467-020-19317-4. Nat Commun. 2020. PMID: 33139698 Free PMC article.

3

The emerging nontraditional roles for tau in the brain.

Tseng JH, Cohen TJ. Tseng JH, et al. Among authors: cohen tj. Cytoskeleton (Hoboken). 2024 Jan;81(1):89-94. doi: 10.1002/cm.21811. Epub 2023 Dec 8. Cytoskeleton (Hoboken). 2024. PMID: 38063261 Free PMC article. No abstract available.

4

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies.

Irwin DJ, Cohen TJ, Grossman M, Arnold SE, Xie SX, Lee VM, Trojanowski JQ. Irwin DJ, et al. Among authors: cohen tj. Brain. 2012 Mar;135(Pt 3):807-18. doi: 10.1093/brain/aws013. Brain. 2012. PMID: 22366796 Free PMC article.

5

Acetylated tau neuropathology in sporadic and hereditary tauopathies.

Irwin DJ, Cohen TJ, Grossman M, Arnold SE, McCarty-Wood E, Van Deerlin VM, Lee VM, Trojanowski JQ. Irwin DJ, et al. Among authors: cohen tj. Am J Pathol. 2013 Aug;183(2):344-51. doi: 10.1016/j.ajpath.2013.04.025. Am J Pathol. 2013. PMID: 23885714 Free PMC article.

6

A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy.

Trzeciakiewicz H, Tseng JH, Wander CM, Madden V, Tripathy A, Yuan CX, Cohen TJ. Trzeciakiewicz H, et al. Among authors: cohen tj. Sci Rep. 2017 Mar 13;7:44102. doi: 10.1038/srep44102. Sci Rep. 2017. PMID: 28287136 Free PMC article.

7

The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology.

Tseng JH, Xie L, Song S, Xie Y, Allen L, Ajit D, Hong JS, Chen X, Meeker RB, Cohen TJ. Tseng JH, et al. Among authors: cohen tj. Cell Rep. 2017 Aug 29;20(9):2169-2183. doi: 10.1016/j.celrep.2017.07.082. Cell Rep. 2017. PMID: 28854366 Free PMC article.

8

A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation.

Ajit D, Trzeciakiewicz H, Tseng JH, Wander CM, Chen Y, Ajit A, King DP, Cohen TJ. Ajit D, et al. Among authors: cohen tj. J Biol Chem. 2019 Nov 8;294(45):16698-16711. doi: 10.1074/jbc.RA119.009674. Epub 2019 Sep 22. J Biol Chem. 2019. PMID: 31543505 Free PMC article.

9

Tau seeds are subject to aberrant modifications resulting in distinct signatures.

Tseng JH, Ajit A, Tabassum Z, Patel N, Tian X, Chen Y, Prevatte AW, Ling K, Rigo F, Meeker RB, Herring LE, Cohen TJ. Tseng JH, et al. Among authors: cohen tj. Cell Rep. 2021 Apr 27;35(4):109037. doi: 10.1016/j.celrep.2021.109037. Cell Rep. 2021. PMID: 33910013 Free PMC article.

10

Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems.

Quiroga IY, Cruikshank AE, Bond ML, Reed KSM, Evangelista BA, Tseng JH, Ragusa JV, Meeker RB, Won H, Cohen S, Cohen TJ, Phanstiel DH. Quiroga IY, et al. Among authors: cohen tj, cohen s. J Neuroinflammation. 2022 Apr 23;19(1):99. doi: 10.1186/s12974-022-02459-1. J Neuroinflammation. 2022. PMID: 35459147 Free PMC article.

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