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Page 1
Somatic mitochondrial DNA mutations are a source of heterogeneity among primary leukemic cells.
McCastlain K, Welsh C, Ni Y, Ding L, Franco M, Autry R, Sejdiu B, Chang TC, Chen W, Wu H, Pan Q, Gonzalez-Pena V, Schreiner P, Arunachalam S, Joo J, Li B, Shen S, Brady S, Zhang J, Gawad C, Evans W, Babu MM, Khrapko K, Wu G, Yu J, Pounds S, Kundu M. McCastlain K, et al. Among authors: brady s. medRxiv [Preprint]. 2024 Sep 27:2024.09.26.24314381. doi: 10.1101/2024.09.26.24314381. medRxiv. 2024. PMID: 39398996 Free PMC article. Preprint.
Heterogeneity of IKZF1 genomic alterations and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia.
Mullighan C, Wangondu R, Ashcraft E, Chang TC, Roberts K, Brady S, Fan Y, Evans W, Relling M, Crews K, Yang J, Yang W, Pounds S, Wu G, Devidas M, Maloney K, Mattano L Jr, Schore R, Angiolillo A, Larsen E, Salzer W, Burke M, Loh M, Jeha S, Pui CH, Inaba H, Cheng C. Mullighan C, et al. Among authors: brady s. Res Sq [Preprint]. 2024 Nov 11:rs.3.rs-5292018. doi: 10.21203/rs.3.rs-5292018/v1. Res Sq. 2024. PMID: 39606455 Free PMC article. Preprint.
Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.
Li B, Brady SW, Ma X, Shen S, Zhang Y, Li Y, Szlachta K, Dong L, Liu Y, Yang F, Wang N, Flasch DA, Myers MA, Mulder HL, Ding L, Liu Y, Tian L, Hagiwara K, Xu K, Zhou X, Sioson E, Wang T, Yang L, Zhao J, Zhang H, Shao Y, Sun H, Sun L, Cai J, Sun HY, Lin TN, Du L, Li H, Rusch M, Edmonson MN, Easton J, Zhu X, Zhang J, Cheng C, Raphael BJ, Tang J, Downing JR, Alexandrov LB, Zhou BS, Pui CH, Yang JJ, Zhang J. Li B, et al. Among authors: brady sw. Blood. 2020 Jan 2;135(1):41-55. doi: 10.1182/blood.2019002220. Blood. 2020. PMID: 31697823 Free PMC article.
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms.
Schwartz JR, Ma J, Kamens J, Westover T, Walsh MP, Brady SW, Robert Michael J, Chen X, Montefiori L, Song G, Wu G, Wu H, Branstetter C, Hiltenbrand R, Walsh MF, Nichols KE, Maciaszek JL, Liu Y, Kumar P, Easton J, Newman S, Rubnitz JE, Mullighan CG, Pounds S, Zhang J, Gruber T, Ma X, Klco JM. Schwartz JR, et al. Among authors: brady sw. Nat Commun. 2021 Feb 12;12(1):985. doi: 10.1038/s41467-021-21255-8. Nat Commun. 2021. PMID: 33579957 Free PMC article.
Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse.
Yang F, Brady SW, Tang C, Sun H, Du L, Barz MJ, Ma X, Chen Y, Fang H, Li X, Kolekar P, Pathak O, Cai J, Ding L, Wang T, von Stackelberg A, Shen S, Eckert C, Klco JM, Chen H, Duan C, Liu Y, Li H, Li B, Kirschner-Schwabe R, Zhang J, Zhou BS. Yang F, et al. Among authors: brady sw. Nat Cancer. 2021 Aug;2(8):819-834. doi: 10.1038/s43018-021-00230-8. Epub 2021 Jul 22. Nat Cancer. 2021. PMID: 35122027
Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor.
Arunachalam S, Szlachta K, Brady SW, Ma X, Ju B, Shaner B, Mulder HL, Easton J, Raphael BJ, Myers M, Tinkle C, Allen SJ, Orr BA, Wetmore CJ, Baker SJ, Zhang J. Arunachalam S, et al. Among authors: brady sw. Acta Neuropathol Commun. 2022 May 31;10(1):80. doi: 10.1186/s40478-022-01381-0. Acta Neuropathol Commun. 2022. PMID: 35642016 Free PMC article.
The genomic landscape of pediatric acute lymphoblastic leukemia.
Brady SW, Roberts KG, Gu Z, Shi L, Pounds S, Pei D, Cheng C, Dai Y, Devidas M, Qu C, Hill AN, Payne-Turner D, Ma X, Iacobucci I, Baviskar P, Wei L, Arunachalam S, Hagiwara K, Liu Y, Flasch DA, Liu Y, Parker M, Chen X, Elsayed AH, Pathak O, Li Y, Fan Y, Michael JR, Rusch M, Wilkinson MR, Foy S, Hedges DJ, Newman S, Zhou X, Wang J, Reilly C, Sioson E, Rice SV, Pastor Loyola V, Wu G, Rampersaud E, Reshmi SC, Gastier-Foster J, Guidry Auvil JM, Gesuwan P, Smith MA, Winick N, Carroll AJ, Heerema NA, Harvey RC, Willman CL, Larsen E, Raetz EA, Borowitz MJ, Wood BL, Carroll WL, Zweidler-McKay PA, Rabin KR, Mattano LA, Maloney KW, Winter SS, Burke MJ, Salzer W, Dunsmore KP, Angiolillo AL, Crews KR, Downing JR, Jeha S, Pui CH, Evans WE, Yang JJ, Relling MV, Gerhard DS, Loh ML, Hunger SP, Zhang J, Mullighan CG. Brady SW, et al. Nat Genet. 2022 Sep;54(9):1376-1389. doi: 10.1038/s41588-022-01159-z. Epub 2022 Sep 1. Nat Genet. 2022. PMID: 36050548 Free PMC article.
The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment.
Brady SW, Ma X, Bahrami A, Satas G, Wu G, Newman S, Rusch M, Putnam DK, Mulder HL, Yergeau DA, Edmonson MN, Easton J, Alexandrov LB, Chen X, Mardis ER, Wilson RK, Downing JR, Pappo AS, Raphael BJ, Dyer MA, Zhang J. Brady SW, et al. Mol Cancer Res. 2019 Apr;17(4):895-906. doi: 10.1158/1541-7786.MCR-18-0620. Epub 2019 Jan 16. Mol Cancer Res. 2019. PMID: 30651371 Free PMC article.
1,362 results