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Page 1
Radiomultiomics: quantitative CT clusters of severe asthma associated with multiomics.
Zounemat Kermani N, Chung KF, Macis G, Santini G, Clemeno FAA, Versi A, Sun K, Abdel-Aziz MI, Andersson LI, Auffray C, Badi Y, Bakke P, Brightling C, Brinkman P, Caruso M, Chanez P, De Meulder B, Djukanovic R, Fabbri L, Fowler SJ, Horvath I, Howarth P, James AJ, Kolmert J, Kraft M, Li CX, Maitland-van der Zee AH, Malerba M, Papi A, Rabe K, Sanak M, Shaw DE, Singh D, Sparreman Mikus M, van Den Berge M, Wheelock AM, Wheelock CE, Yasinska V, Guo YK, Wagers S, Barnes PJ, Bush A, Sterk PJ, Dahlen SE, Adcock IM, Siddiqui S, Montuschi P; U-BIOPRED and ATLANTIS Study Groups. Zounemat Kermani N, et al. Among authors: sun k. Eur Respir J. 2024 Nov 21;64(5):2400207. doi: 10.1183/13993003.00207-2024. Print 2024 Nov. Eur Respir J. 2024. PMID: 39401856 Free PMC article.
Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study.
Wilson SJ, Ward JA, Sousa AR, Corfield J, Bansal AT, De Meulder B, Lefaudeux D, Auffray C, Loza MJ, Baribaud F, Fitch N, Sterk PJ, Chung KF, Gibeon D, Sun K, Guo YK, Adcock I, Djukanovic R, Dahlen B, Chanez P, Shaw D, Krug N, Hohlfeld J, Sandström T, Howarth PH; U-BIOPRED Study Group. Wilson SJ, et al. Among authors: sun k. Eur Respir J. 2016 Nov;48(5):1307-1319. doi: 10.1183/13993003.01129-2016. Epub 2016 Oct 6. Eur Respir J. 2016. PMID: 27799384 Free article.
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma.
Hekking PP, Loza MJ, Pavlidis S, De Meulder B, Lefaudeux D, Baribaud F, Auffray C, Wagener AH, Brinkman P, Lutter R, Bansal AT, Sousa AR, Bates SA, Pandis I, Fleming LJ, Shaw DE, Fowler SJ, Guo Y, Meiser A, Sun K, Corfield J, Howarth P, Bel EH, Adcock IM, Chung KF, Djukanovic R, Sterk PJ; U-BIOPRED Study Group. Hekking PP, et al. Among authors: sun k. Eur Respir J. 2017 Sep 27;50(3):1602298. doi: 10.1183/13993003.02298-2016. Print 2017 Sep. Eur Respir J. 2017. PMID: 28954779 Free article.
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.
Takahashi K, Pavlidis S, Ng Kee Kwong F, Hoda U, Rossios C, Sun K, Loza M, Baribaud F, Chanez P, Fowler SJ, Horvath I, Montuschi P, Singer F, Musial J, Dahlen B, Dahlen SE, Krug N, Sandstrom T, Shaw DE, Lutter R, Bakke P, Fleming LJ, Howarth PH, Caruso M, Sousa AR, Corfield J, Auffray C, De Meulder B, Lefaudeux D, Djukanovic R, Sterk PJ, Guo Y, Adcock IM, Chung KF; , on behalf of the U-BIOPRED study group. Takahashi K, et al. Among authors: sun k. Eur Respir J. 2018 May 3;51(5):1702173. doi: 10.1183/13993003.02173-2017. Print 2018 May. Eur Respir J. 2018. PMID: 29650557 Free article.
"T2-high" in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin.
Pavlidis S, Takahashi K, Ng Kee Kwong F, Xie J, Hoda U, Sun K, Elyasigomari V, Agapow P, Loza M, Baribaud F, Chanez P, Fowler SJ, Shaw DE, Fleming LJ, Howarth PH, Sousa AR, Corfield J, Auffray C, De Meulder B, Knowles R, Sterk PJ, Guo Y, Adcock IM, Djukanovic R, Fan Chung K; on behalf of the U-BIOPRED Study Group. Pavlidis S, et al. Among authors: sun k. Eur Respir J. 2019 Jan 3;53(1):1800938. doi: 10.1183/13993003.00938-2018. Print 2019 Jan. Eur Respir J. 2019. PMID: 30578390 Free article.
Instability of sputum molecular phenotypes in U-BIOPRED severe asthma.
Kermani NZ, Pavlidis S, Xie J, Sun K, Loza M, Baribaud F, Fowler SJ, Shaw DE, Fleming LJ, Howarth PH, Sousa AR, Corfield J, Auffray C, De Meulder B, Sterk PJ, Guo Y, Uddin M, Djukanovic R, Adcock IM, Chung KF; U-BIOPRED study group. Kermani NZ, et al. Among authors: sun k. Eur Respir J. 2021 Feb 4;57(2):2001836. doi: 10.1183/13993003.01836-2020. Print 2021 Feb. Eur Respir J. 2021. PMID: 33008937 Free PMC article.
Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma.
Kermani NZ, Song WJ, Badi Y, Versi A, Guo Y, Sun K, Bhavsar P, Howarth P, Dahlen SE, Sterk PJ, Djukanovic R, Adcock IM, Chung KF; U-BIOPRED Consortium. Kermani NZ, et al. Among authors: sun k. Respir Res. 2021 Jan 7;22(1):10. doi: 10.1186/s12931-020-01605-8. Respir Res. 2021. PMID: 33413387 Free PMC article.
A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes.
Abdel-Aziz MI, Vijverberg SJH, Neerincx AH, Brinkman P, Wagener AH, Riley JH, Sousa AR, Bates S, Wagers SS, De Meulder B, Auffray C, Wheelock ÅM, Bansal AT, Caruso M, Chanez P, Uddin M, Corfield J, Horvath I, Krug N, Musial J, Sun K, Shaw DE, Sandström T, Montuschi P, Fowler SJ, Lutter R, Djukanovic R, Howarth P, Skipp P, Sanak M, Adcock IM, Chung KF, Sterk PJ, Kraneveld AD, Maitland-van der Zee AH; U-BIOPRED Study Group. Abdel-Aziz MI, et al. Among authors: sun k. Eur Respir J. 2022 Jan 13;59(1):2102603. doi: 10.1183/13993003.02603-2021. Print 2022 Jan. Eur Respir J. 2022. PMID: 34824056 Free article. No abstract available.
Endotypes of severe neutrophilic and eosinophilic asthma from multi-omics integration of U-BIOPRED sputum samples.
Kermani NZ, Li CX, Versi A, Badi Y, Sun K, Abdel-Aziz MI, Bonatti M, Maitland-van der Zee AH, Djukanovic R, Wheelock Å, Dahlen SE, Howarth P, Guo Y, Chung KF, Adcock IM; U‐BIOPRED Project Team. Kermani NZ, et al. Among authors: sun k. Clin Transl Med. 2024 Jul;14(7):e1771. doi: 10.1002/ctm2.1771. Clin Transl Med. 2024. PMID: 39073027 Free PMC article.
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
Lefaudeux D, De Meulder B, Loza MJ, Peffer N, Rowe A, Baribaud F, Bansal AT, Lutter R, Sousa AR, Corfield J, Pandis I, Bakke PS, Caruso M, Chanez P, Dahlén SE, Fleming LJ, Fowler SJ, Horvath I, Krug N, Montuschi P, Sanak M, Sandstrom T, Shaw DE, Singer F, Sterk PJ, Roberts G, Adcock IM, Djukanovic R, Auffray C, Chung KF; U-BIOPRED Study Group. Lefaudeux D, et al. J Allergy Clin Immunol. 2017 Jun;139(6):1797-1807. doi: 10.1016/j.jaci.2016.08.048. Epub 2016 Oct 20. J Allergy Clin Immunol. 2017. PMID: 27773852 Free article.
7,550 results