Parhami F - Search Results

1

Anti-Inflammatory Oxysterol, Oxy210, Inhibits Atherosclerosis in Hyperlipidemic Mice and Inflammatory Responses of Vascular Cells.

Stappenbeck F, Wang F, Sinha SK, Hui ST, Farahi L, Mukhamedova N, Fleetwood A, Murphy AJ, Sviridov D, Lusis AJ, Parhami F. Stappenbeck F, et al. Among authors: parhami f. Cells. 2024 Sep 30;13(19):1632. doi: 10.3390/cells13191632. Cells. 2024. PMID: 39404395 Free PMC article.

2

Inhibition of Hedgehog Signaling in Fibroblasts, Pancreatic, and Lung Tumor Cells by Oxy186, an Oxysterol Analogue with Drug-Like Properties.

Wang F, Stappenbeck F, Parhami F. Wang F, et al. Among authors: parhami f. Cells. 2019 May 27;8(5):509. doi: 10.3390/cells8050509. Cells. 2019. PMID: 31137846 Free PMC article.

3

Inhibition of Non-Small Cell Lung Cancer Cells by Oxy210, an Oxysterol-Derivative that Antagonizes TGFβ and Hedgehog Signaling.

Stappenbeck F, Wang F, Tang LY, Zhang YE, Parhami F. Stappenbeck F, et al. Among authors: parhami f. Cells. 2019 Oct 22;8(10):1297. doi: 10.3390/cells8101297. Cells. 2019. PMID: 31652618 Free PMC article.

4

Oxy210, a novel inhibitor of hedgehog and TGF-β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice.

Hui ST, Wang F, Stappenbeck F, French SW, Magyar CE, Parhami F, Lusis AJ. Hui ST, et al. Among authors: parhami f. Endocrinol Diabetes Metab. 2021 Oct;4(4):e00296. doi: 10.1002/edm2.296. Epub 2021 Aug 31. Endocrinol Diabetes Metab. 2021. PMID: 34505423 Free PMC article.

5

Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization.

Wang F, Stappenbeck F, Tang LY, Zhang YE, Hui ST, Lusis AJ, Parhami F. Wang F, et al. Among authors: parhami f. Int J Mol Sci. 2022 May 13;23(10):5478. doi: 10.3390/ijms23105478. Int J Mol Sci. 2022. PMID: 35628290 Free PMC article.

6

Oxy210, a Semi-Synthetic Oxysterol, Inhibits Profibrotic Signaling in Cellular Models of Lung and Kidney Fibrosis.

Wang F, Stappenbeck F, Parhami F. Wang F, et al. Among authors: parhami f. Pharmaceuticals (Basel). 2023 Jan 12;16(1):114. doi: 10.3390/ph16010114. Pharmaceuticals (Basel). 2023. PMID: 36678611 Free PMC article.

7

Inhibition of Pancreatic Cancer Cell-Induced Paracrine Hedgehog Signaling by Liver X Receptor Agonists and Oxy16, a Naturally Occurring Oxysterol.

Wang F, Stappenbeck F, Matsui W, Parhami F. Wang F, et al. Among authors: parhami f. J Cell Biochem. 2017 Mar;118(3):499-509. doi: 10.1002/jcb.25668. Epub 2016 Sep 21. J Cell Biochem. 2017. PMID: 27490478 Free PMC article.

8

Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer.

Tang LY, Spezia M, Chen T, Shin JH, Wang F, Stappenbeck F, Lebensohn AM, Parhami F, Zhang YE. Tang LY, et al. Among authors: parhami f. Cell Biosci. 2022 Jul 30;12(1):119. doi: 10.1186/s13578-022-00857-9. Cell Biosci. 2022. PMID: 35908024 Free PMC article.

9

Identification of Anti-Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Oxysterol Derivatives In Vitro.

Ohashi H, Wang F, Stappenbeck F, Tsuchimoto K, Kobayashi C, Saso W, Kataoka M, Yamasaki M, Kuramochi K, Muramatsu M, Suzuki T, Sureau C, Takeda M, Wakita T, Parhami F, Watashi K. Ohashi H, et al. Among authors: parhami f. Int J Mol Sci. 2021 Mar 19;22(6):3163. doi: 10.3390/ijms22063163. Int J Mol Sci. 2021. PMID: 33808940 Free PMC article.

10

Effect of Oxy133, an osteogenic oxysterol, on new bone formation in rat two-level posterolateral fusion model.

Buser Z, Drapeau S, Stappenbeck F, Pereira RC, Parhami F, Wang JC. Buser Z, et al. Among authors: parhami f. Eur Spine J. 2017 Nov;26(11):2763-2772. doi: 10.1007/s00586-017-5149-9. Epub 2017 May 25. Eur Spine J. 2017. PMID: 28547574

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