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CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation.
Raynor JL, Collins N, Shi H, Guy C, Saravia J, Ah Lim S, Chapman NM, Zhou P, Wang Y, Sun Y, Risch I, Hu H, Kc A, Sun R, Shrestha S, Huang H, Connelly JP, Pruett-Miller SM, Reina-Campos M, Goldrath AW, Belkaid Y, Chi H. Raynor JL, et al. Among authors: goldrath aw. Immunity. 2024 Nov 12;57(11):2597-2614.e13. doi: 10.1016/j.immuni.2024.09.013. Epub 2024 Oct 14. Immunity. 2024. PMID: 39406246 Free PMC article.
Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted.
Reina-Campos M, Monell A, Ferry A, Luna V, Cheung KP, Galletti G, Scharping NE, Takehara KK, Quon S, Boland B, Lin YH, Wong WH, Indralingam CS, Yeo GW, Chang JT, Heeg M, Goldrath AW. Reina-Campos M, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2024 Mar 25:2024.03.20.585130. doi: 10.1101/2024.03.20.585130. bioRxiv. 2024. PMID: 38585842 Free PMC article. Preprint.
Active maintenance of CD8+ T cell naivety through regulation of global genome architecture.
Russ BE, Barugahare A, Dakle P, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, See M, Nussing S, Morey AE, Udupa VA, Bennett TJ, Kallies A, Murre C, Collas P, Powell D, Goldrath AW, Turner SJ. Russ BE, et al. Among authors: goldrath aw. Cell Rep. 2023 Oct 31;42(10):113301. doi: 10.1016/j.celrep.2023.113301. Epub 2023 Oct 19. Cell Rep. 2023. PMID: 37858463 Free PMC article.
Active maintenance of CD8+ T cell naïvety through regulation of global genome architecture.
Russ BE, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, Barugahare A, See M, Nussing S, Morey AE, Udupa VA, Bennett TJ, Kallies A, Murre C, Collas P, Powell D, Goldrath AW, Turner SJ. Russ BE, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2023 Feb 27:2023.02.26.530139. doi: 10.1101/2023.02.26.530139. bioRxiv. 2023. Update in: Cell Rep. 2023 Oct 31;42(10):113301. doi: 10.1016/j.celrep.2023.113301 PMID: 36909629 Free PMC article. Updated. Preprint.
Molecular definition of the identity and activation of natural killer cells.
Bezman NA, Kim CC, Sun JC, Min-Oo G, Hendricks DW, Kamimura Y, Best JA, Goldrath AW, Lanier LL; Immunological Genome Project Consortium. Bezman NA, et al. Among authors: goldrath aw. Nat Immunol. 2012 Oct;13(10):1000-9. doi: 10.1038/ni.2395. Epub 2012 Aug 19. Nat Immunol. 2012. PMID: 22902830 Free PMC article.
Systemic inflammation and lymphocyte activation precede rheumatoid arthritis.
He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen K, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA. He Z, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2024 Nov 12:2024.10.25.620344. doi: 10.1101/2024.10.25.620344. bioRxiv. 2024. PMID: 39554042 Free PMC article. Preprint.
Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults.
Gong Q, Sharma M, Kuan EL, Glass MC, Chander A, Singh M, Graybuck LT, Thomson ZJ, LaFrance CM, Zaim SR, Peng T, Okada LY, Genge PC, Henderson KE, Dornisch EM, Layton ED, Wittig PJ, Heubeck AT, Mukuka NM, Reading J, Roll CR, Hernandez V, Parthasarathy V, Stuckey TJ, Musgrove B, Swanson E, Lord C, Weiss MDA, Phalen CG, Mettey RR, Lee KJ, Johanneson JB, Kawelo EK, Garber J, Krishnan U, Smithmyer M, Wherry EJ, Vella L, Henrickson SE, Kopp MS, Savage AK, Becker LA, Meijer P, Coffey EM, Goronzy JJ, Speake C, Bumol TF, Goldrath AW, Torgerson TR, Li XJ, Skene PJ, Buckner JH, Gustafson CE. Gong Q, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2024 Sep 14:2024.09.10.612119. doi: 10.1101/2024.09.10.612119. bioRxiv. 2024. PMID: 39314416 Free PMC article. Preprint.
Metabolic programs of T cell tissue residency empower tumour immunity.
Reina-Campos M, Heeg M, Kennewick K, Mathews IT, Galletti G, Luna V, Nguyen Q, Huang H, Milner JJ, Hu KH, Vichaidit A, Santillano N, Boland BS, Chang JT, Jain M, Sharma S, Krummel MF, Chi H, Bensinger SJ, Goldrath AW. Reina-Campos M, et al. Among authors: goldrath aw. Nature. 2023 Sep;621(7977):179-187. doi: 10.1038/s41586-023-06483-w. Epub 2023 Aug 30. Nature. 2023. PMID: 37648857 Free PMC article.
108 results