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CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation.
Raynor JL, Collins N, Shi H, Guy C, Saravia J, Ah Lim S, Chapman NM, Zhou P, Wang Y, Sun Y, Risch I, Hu H, Kc A, Sun R, Shrestha S, Huang H, Connelly JP, Pruett-Miller SM, Reina-Campos M, Goldrath AW, Belkaid Y, Chi H. Raynor JL, et al. Among authors: sun r, sun y. Immunity. 2024 Nov 12;57(11):2597-2614.e13. doi: 10.1016/j.immuni.2024.09.013. Epub 2024 Oct 14. Immunity. 2024. PMID: 39406246 Free PMC article.
PTEN directs developmental and metabolic signaling for innate-like T cell fate and tissue homeostasis.
Blanco DB, Chapman NM, Raynor JL, Xu C, Su W, Kc A, Li W, Lim SA, Schattgen S, Shi H, Risch I, Sun Y, Dhungana Y, Kim Y, Wei J, Rankin S, Neale G, Thomas PG, Yang K, Chi H. Blanco DB, et al. Among authors: sun y. Nat Cell Biol. 2022 Nov;24(11):1642-1654. doi: 10.1038/s41556-022-01011-w. Epub 2022 Oct 27. Nat Cell Biol. 2022. PMID: 36302969 Free PMC article.
SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity.
Guo C, You Z, Shi H, Sun Y, Du X, Palacios G, Guy C, Yuan S, Chapman NM, Lim SA, Sun X, Saravia J, Rankin S, Dhungana Y, Chi H. Guo C, et al. Among authors: sun y, sun x. Nature. 2023 Aug;620(7972):200-208. doi: 10.1038/s41586-023-06299-8. Epub 2023 Jul 5. Nature. 2023. PMID: 37407815 Free PMC article.
CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer's disease pathology.
Su W, Saravia J, Risch I, Rankin S, Guy C, Chapman NM, Shi H, Sun Y, Kc A, Li W, Huang H, Lim SA, Hu H, Wang Y, Liu D, Jiao Y, Chen PC, Soliman H, Yan KK, Zhang J, Vogel P, Liu X, Serrano GE, Beach TG, Yu J, Peng J, Chi H. Su W, et al. Among authors: sun y. Nat Immunol. 2023 Oct;24(10):1735-1747. doi: 10.1038/s41590-023-01604-z. Epub 2023 Sep 7. Nat Immunol. 2023. PMID: 37679549 Free PMC article.
SequencErr: measuring and suppressing sequencer errors in next-generation sequencing data.
Davis EM, Sun Y, Liu Y, Kolekar P, Shao Y, Szlachta K, Mulder HL, Ren D, Rice SV, Wang Z, Nakitandwe J, Gout AM, Shaner B, Hall S, Robison LL, Pounds S, Klco JM, Easton J, Ma X. Davis EM, et al. Among authors: sun y. Genome Biol. 2021 Jan 25;22(1):37. doi: 10.1186/s13059-020-02254-2. Genome Biol. 2021. PMID: 33487172 Free PMC article.
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