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Page 1
Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis.
More S, Bonnereau J, Wouters D, Spotbeen X, Karras P, Rizzollo F, Killian T, Venken T, Naulaerts S, Vervoort E, Ganne M, Nittner D, Verhoeven J, Bechter O, Bosisio F, Lambrechts D, Sifrim A, Stockwell BR, Swinnen JV, Marine JC, Agostinis P. More S, et al. Among authors: agostinis p. Sci Adv. 2024 Oct 18;10(42):eadp6164. doi: 10.1126/sciadv.adp6164. Epub 2024 Oct 16. Sci Adv. 2024. PMID: 39413195 Free article.
Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics.
Garg AD, More S, Rufo N, Mece O, Sassano ML, Agostinis P, Zitvogel L, Kroemer G, Galluzzi L. Garg AD, et al. Among authors: agostinis p. Oncoimmunology. 2017 Oct 4;6(12):e1386829. doi: 10.1080/2162402X.2017.1386829. eCollection 2017. Oncoimmunology. 2017. PMID: 29209573 Free PMC article. Review.
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.
Talebi A, Dehairs J, Rambow F, Rogiers A, Nittner D, Derua R, Vanderhoydonc F, Duarte JAG, Bosisio F, Van den Eynde K, Nys K, Pérez MV, Agostinis P, Waelkens E, Van den Oord J, Fendt SM, Marine JC, Swinnen JV. Talebi A, et al. Among authors: agostinis p. Nat Commun. 2018 Jun 27;9(1):2500. doi: 10.1038/s41467-018-04664-0. Nat Commun. 2018. PMID: 29950559 Free PMC article.
ATP13A2 deficiency disrupts lysosomal polyamine export.
van Veen S, Martin S, Van den Haute C, Benoy V, Lyons J, Vanhoutte R, Kahler JP, Decuypere JP, Gelders G, Lambie E, Zielich J, Swinnen JV, Annaert W, Agostinis P, Ghesquière B, Verhelst S, Baekelandt V, Eggermont J, Vangheluwe P. van Veen S, et al. Among authors: agostinis p. Nature. 2020 Feb;578(7795):419-424. doi: 10.1038/s41586-020-1968-7. Epub 2020 Jan 29. Nature. 2020. PMID: 31996848
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.
Hamouda NN, Van den Haute C, Vanhoutte R, Sannerud R, Azfar M, Mayer R, Cortés Calabuig Á, Swinnen JV, Agostinis P, Baekelandt V, Annaert W, Impens F, Verhelst SHL, Eggermont J, Martin S, Vangheluwe P. Hamouda NN, et al. Among authors: agostinis p. J Biol Chem. 2021 Jan-Jun;296:100182. doi: 10.1074/jbc.RA120.013908. Epub 2020 Dec 17. J Biol Chem. 2021. PMID: 33310703 Free PMC article.
Endothelial cell autophagy in homeostasis and cancer.
Verhoeven J, Baelen J, Agrawal M, Agostinis P. Verhoeven J, et al. Among authors: agostinis p. FEBS Lett. 2021 Jun;595(11):1497-1511. doi: 10.1002/1873-3468.14087. Epub 2021 Apr 24. FEBS Lett. 2021. PMID: 33837545 Free article. Review.
BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
Vara-Pérez M, Rossi M, Van den Haute C, Maes H, Sassano ML, Venkataramani V, Michalke B, Romano E, Rillaerts K, Garg AD, Schepkens C, Bosisio FM, Wouters J, Oliveira AI, Vangheluwe P, Annaert W, Swinnen JV, Colet JM, van den Oord JJ, Fendt SM, Mazzone M, Agostinis P. Vara-Pérez M, et al. Among authors: agostinis p. EMBO J. 2021 May 17;40(10):e106214. doi: 10.15252/embj.2020106214. Epub 2021 May 1. EMBO J. 2021. PMID: 33932034 Free PMC article.
272 results