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PET clinical study of novel antipsychotic LB-102 demonstrates unexpectedly prolonged dopamine receptor target engagement.
Wong DF, Chand GB, Caito N, Eramo A, Grattan VT, Hixon MS, Nicol G, Lessie E, Prensky Z, Kuwabara H, Tian L, Valenta I, Schindler TH, Gründer G, Vaino AR. Wong DF, et al. Neuropsychopharmacology. 2024 Dec;50(2):372-377. doi: 10.1038/s41386-024-01951-x. Epub 2024 Oct 16. Neuropsychopharmacology. 2024. PMID: 39414986 Free PMC article. Clinical Trial.
Time course of 5-HT2A receptor occupancy in the human brain after a single oral dose of the putative antipsychotic drug MDL 100,907 measured by positron emission tomography.
Gründer G, Yokoi F, Offord SJ, Ravert HT, Dannals RF, Salzmann JK, Szymanski S, Wilson PD, Howard DR, Wong DF. Gründer G, et al. Among authors: wong df. Neuropsychopharmacology. 1997 Sep;17(3):175-85. doi: 10.1016/S0893-133X(97)00044-4. Neuropsychopharmacology. 1997. PMID: 9272484
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving.
Wong DF, Kuwabara H, Schretlen DJ, Bonson KR, Zhou Y, Nandi A, Brasić JR, Kimes AS, Maris MA, Kumar A, Contoreggi C, Links J, Ernst M, Rousset O, Zukin S, Grace AA, Lee JS, Rohde C, Jasinski DR, Gjedde A, London ED. Wong DF, et al. Neuropsychopharmacology. 2006 Dec;31(12):2716-27. doi: 10.1038/sj.npp.1301194. Epub 2006 Sep 13. Neuropsychopharmacology. 2006. PMID: 16971900
Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET.
Wong DF, Brasić JR, Singer HS, Schretlen DJ, Kuwabara H, Zhou Y, Nandi A, Maris MA, Alexander M, Ye W, Rousset O, Kumar A, Szabo Z, Gjedde A, Grace AA. Wong DF, et al. Neuropsychopharmacology. 2008 May;33(6):1239-51. doi: 10.1038/sj.npp.1301528. Epub 2007 Nov 7. Neuropsychopharmacology. 2008. PMID: 17987065 Free PMC article. Clinical Trial.
438 results