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Cryo-EM visualizes multiple steps of dynein's activation pathway.
Kendrick AA, Nguyen KHV, Ma W, Karasmanis EP, Amaro RE, Reck-Peterson SL, Leschziner AE. Kendrick AA, et al. bioRxiv [Preprint]. 2024 Oct 13:2024.09.28.615567. doi: 10.1101/2024.09.28.615567. bioRxiv. 2024. PMID: 39416051 Free PMC article. Preprint.
Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Karasmanis EP, Reimer JM, Kendrick AA, Nguyen KHV, Rodriguez JA, Truong JB, Lahiri I, Reck-Peterson SL, Leschziner AE. Karasmanis EP, et al. Among authors: kendrick aa. Nat Struct Mol Biol. 2023 Sep;30(9):1357-1364. doi: 10.1038/s41594-023-01069-6. Epub 2023 Aug 24. Nat Struct Mol Biol. 2023. PMID: 37620585 Free PMC article.
HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity.
Saeedi BJ, Kao DJ, Kitzenberg DA, Dobrinskikh E, Schwisow KD, Masterson JC, Kendrick AA, Kelly CJ, Bayless AJ, Kominsky DJ, Campbell EL, Kuhn KA, Furuta GT, Colgan SP, Glover LE. Saeedi BJ, et al. Among authors: kendrick aa. Mol Biol Cell. 2015 Jun 15;26(12):2252-62. doi: 10.1091/mbc.E14-07-1194. Epub 2015 Apr 22. Mol Biol Cell. 2015. PMID: 25904334 Free PMC article.
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