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Page 1
Characterization of cell states in biliary tract cancers identifies mechanisms of therapeutic resistance in a phase II trial of DKN-01/nivolumab.
Park RJ, Parikh M, Pappas L, Sade-Feldman M, Kulkarni AS, Bi L, LaSalle TJ, Galway A, Kuhlman C, Blaszkowsky LS, Meyerhardt JA, Enzinger PC, Biller L, Allen JN, Kagey MH, Baum J, Sirard C, Duda DG, Zhu AX, Abrams TA, Hacohen N, Ting DT, Mehta A, Goyal L. Park RJ, et al. Among authors: ting dt. medRxiv [Preprint]. 2024 Oct 8:2024.10.08.24315092. doi: 10.1101/2024.10.08.24315092. medRxiv. 2024. PMID: 39417106 Free PMC article. Preprint.
Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product.
Mishra A, Huang SB, Dubash T, Burr R, Edd JF, Wittner BS, Cunneely QE, Putaturo VR, Deshpande A, Antmen E, Gopinathan KA, Otani K, Miyazawa Y, Kwak JE, Guay SY, Kelly J, Walsh J, Nieman L, Galler I, Chan P, Lawrence MS, Sullivan RJ, Bardia A, Micalizzi DS, Sequist LV, Lee RJ, Franses JW, Ting DT, Brunker PAR, Maheswaran S, Miyamoto DT, Haber DA, Toner M. Mishra A, et al. Among authors: ting dt. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.583573. doi: 10.1101/2024.03.13.583573. bioRxiv. 2024. PMID: 38559183 Free PMC article. Preprint.
Dysregulated Repeat Element Viral-like Immune Response in Hepatocellular Carcinoma.
Coley AK, Lu C, Pankaj A, Emmett MJ, Lang ER, Song Y, Xu KH, Xu N, Patel BK, Chougule A, Nieman LT, Aryee MJ, Ferrone CR, Deshpande V, Franses JW, Ting DT. Coley AK, et al. Among authors: ting dt. bioRxiv [Preprint]. 2023 Dec 5:2023.12.04.570014. doi: 10.1101/2023.12.04.570014. bioRxiv. 2023. PMID: 38105940 Free PMC article. Preprint.
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.
Sun S, You E, Hong J, Hoyos D, Del Priore I, Tsanov KM, Mattagajasingh O, Di Gioacchino A, Marhon SA, Chacon-Barahona J, Li H, Jiang H, Hozeifi S, Rosas-Bringas O, Xu KH, Song Y, Lang ER, Rojas AS, Nieman LT, Patel BK, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, Zenklusen D, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD. Sun S, et al. Among authors: ting dt. Immunity. 2024 Dec 10;57(12):2879-2894.e11. doi: 10.1016/j.immuni.2024.10.015. Epub 2024 Nov 21. Immunity. 2024. PMID: 39577413 Free article.
Dynamic Evolution of Fibroblasts Revealed by Single-Cell RNA Sequencing of Human Pancreatic Cancer.
Dimitrieva S, Harrison JM, Chang J, Piquet M, Mino-Kenudson M, Gabriel M, Sagar V, Horn H, Lage K, Kim J, Li G, Weng S, Harris C, Kulkarni AS, Ting DT, Qadan M, Fagenholz PJ, Ferrone CR, Grauel AL, Laszewski T, Raza A, Riester M, Somerville T, Wagner JP, Dranoff G, Engelman JA, Kauffmann A, Leary R, Warshaw AL, Lillemoe KD, Fernández-Del Castillo C, Ruddy DA, Liss AS, Cremasco V. Dimitrieva S, et al. Among authors: ting dt. Cancer Res Commun. 2024 Dec 1;4(12):3049-3066. doi: 10.1158/2767-9764.CRC-23-0489. Cancer Res Commun. 2024. PMID: 39485038 Free PMC article.
Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer.
You E, Danaher P, Lu C, Sun S, Zou L, Phillips IE, Rojas AS, Ho NI, Song Y, Raabe MJ, Xu KH, Richieri PM, Li H, Aston N, Porter RL, Patel BK, Nieman LT, Schurman N, Hudson BM, North K, Church SE, Deshpande V, Liss AS, Kim TK, Cui Y, Kim Y, Greenbaum BD, Aryee MJ, Ting DT. You E, et al. Among authors: ting dt. Cell. 2024 Dec 12;187(25):7232-7247.e23. doi: 10.1016/j.cell.2024.09.024. Epub 2024 Oct 8. Cell. 2024. PMID: 39383862
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies.
Esfahani SA, Ma H, Krishna S, Shuvaev S, Sabbagh M, Deffler C, Rotile N, Weigand-Whittier J, Zhou IY, Catana C, Catalano OA, Ting DT, Heidari P, Abston E, Lanuti M, Boland GM, Pathak P, Roberts H, Tanabe KK, Qadan M, Castillo CF, Shih A, Parikh AR, Weekes CD, Hong TS, Caravan P. Esfahani SA, et al. Among authors: ting dt. Theranostics. 2024 Sep 9;14(15):5745-5761. doi: 10.7150/thno.100116. eCollection 2024. Theranostics. 2024. PMID: 39346545 Free PMC article.
HCC spatial transcriptomic profiling reveals significant and potentially targetable cancer-endothelial interactions.
Lu C, Pankaj A, Raabe M, Nawrocki C, Liu A, Xu N, Patel BK, Emmett MJ, Coley AK, Ferrone CR, Deshpande V, Bhan I, Hoshida Y, Ting DT, Aryee MJ, Franses JW. Lu C, et al. Among authors: ting dt. Hepatol Commun. 2024 Sep 27;8(10):e0533. doi: 10.1097/HC9.0000000000000533. eCollection 2024 Oct 1. Hepatol Commun. 2024. PMID: 39330965 Free PMC article.
Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment.
Shiau C, Cao J, Gong D, Gregory MT, Caldwell NJ, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Bae JW, Zhao R, Schurman N, Barth JL, Ganci ML, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL. Shiau C, et al. Among authors: ting dt. Nat Genet. 2024 Nov;56(11):2466-2478. doi: 10.1038/s41588-024-01890-9. Epub 2024 Sep 3. Nat Genet. 2024. PMID: 39227743
141 results