Simons M - Search Results

1

Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.

Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: simons m. Immunity. 2024 Nov 12;57(11):2651-2668.e12. doi: 10.1016/j.immuni.2024.09.014. Epub 2024 Oct 16. Immunity. 2024. PMID: 39419029 Free article.

2

Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease.

Simons M, Kramer EM, Macchi P, Rathke-Hartlieb S, Trotter J, Nave KA, Schulz JB. Simons M, et al. J Cell Biol. 2002 Apr 15;157(2):327-36. doi: 10.1083/jcb.200110138. Epub 2002 Apr 15. J Cell Biol. 2002. PMID: 11956232 Free PMC article.

3

Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites.

Trajkovic K, Dhaunchak AS, Goncalves JT, Wenzel D, Schneider A, Bunt G, Nave KA, Simons M. Trajkovic K, et al. Among authors: simons m. J Cell Biol. 2006 Mar 13;172(6):937-48. doi: 10.1083/jcb.200509022. Epub 2006 Mar 6. J Cell Biol. 2006. PMID: 16520383 Free PMC article.

4

Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium.

Nawaz S, Kippert A, Saab AS, Werner HB, Lang T, Nave KA, Simons M. Nawaz S, et al. Among authors: simons m. J Neurosci. 2009 Apr 15;29(15):4794-807. doi: 10.1523/JNEUROSCI.3955-08.2009. J Neurosci. 2009. PMID: 19369548 Free PMC article.

5

Cholesterol and myelin biogenesis.

Saher G, Simons M. Saher G, et al. Among authors: simons m. Subcell Biochem. 2010;51:489-508. doi: 10.1007/978-90-481-8622-8_18. Subcell Biochem. 2010. PMID: 20213556 Review.

6

Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system.

Bakhti M, Snaidero N, Schneider D, Aggarwal S, Möbius W, Janshoff A, Eckhardt M, Nave KA, Simons M. Bakhti M, et al. Among authors: simons m. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3143-8. doi: 10.1073/pnas.1220104110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382229 Free PMC article.

7

Oligodendrocytes: Myelination and Axonal Support.

Simons M, Nave KA. Simons M, et al. Cold Spring Harb Perspect Biol. 2015 Jun 22;8(1):a020479. doi: 10.1101/cshperspect.a020479. Cold Spring Harb Perspect Biol. 2015. PMID: 26101081 Free PMC article. Review.

8

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases.

Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M. Weil MT, et al. Among authors: simons m. Cell Rep. 2016 Jul 12;16(2):314-322. doi: 10.1016/j.celrep.2016.06.008. Epub 2016 Jun 23. Cell Rep. 2016. PMID: 27346352 Free PMC article.

9

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin.

Snaidero N, Velte C, Myllykoski M, Raasakka A, Ignatev A, Werner HB, Erwig MS, Möbius W, Kursula P, Nave KA, Simons M. Snaidero N, et al. Among authors: simons m. Cell Rep. 2017 Jan 10;18(2):314-323. doi: 10.1016/j.celrep.2016.12.053. Cell Rep. 2017. PMID: 28076777 Free PMC article.

10

Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2.

Lüders KA, Patzig J, Simons M, Nave KA, Werner HB. Lüders KA, et al. Among authors: simons m. Glia. 2017 Nov;65(11):1762-1776. doi: 10.1002/glia.23193. Epub 2017 Aug 24. Glia. 2017. PMID: 28836307

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